DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5853 and ABCG29

DIOPT Version :9

Sequence 1:	NP_001260309.1	Gene:	CG5853 / 34322	FlyBaseID:	FBgn0032167	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_566543.1	Gene:	ABCG29 / 820881	AraportID:	AT3G16340	Length:	1416	Species:	Arabidopsis thaliana

Alignment Length:	681	Identity:	168/681 - (24%)
Similarity:	309/681 - (45%)	Gaps:	122/681 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 PLE---PVVEEEVHFDTDALNNLPARE------------PVDMEFKELSLTVKL-------GFNR 120
            |||   .||.:|...:..|.|...::.            |:.|.|..::..|.:       |.::
plant   772 PLEKQQAVVSKENTEENRAENGSKSKSIDVKRGMVLPFTPLTMSFDNVNYYVDMPKEMKEQGVSK 836

  Fly   121 GSKEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSGFKTTG-VDGSILLNGRRRDLPSFRRMS 184
            ...::|..|.|.|....|.|:||.|||||:||:|.|:|.||.| ::|.|.::|..:...:|.|:|
plant   837 DKLQLLKEVTGVFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGYIEGDIRISGFPKRQETFARIS 901

  Fly   185 CYITQDDRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIEDILLLLGLYNHDQTLT-----MRL 244
            .|..|:|...|.:||.|::..:|.|:|.:.|:..||...:::::.|:.|.:....:.     ..|
plant   902 GYCEQNDIHSPQVTVKESLIYSAFLRLPKEVTKYEKMRFVDEVMELVELESLKDAVVGLPGITGL 966

  Fly   245 SGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQPTAKLFQ 309
            |..|:|||:||:||:.||:::|:||||:|||:.:...|:..::.....|||::||||||:..:|:
plant   967 STEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFE 1031

  Fly   310 IFDQVYVLS-AGNCVYQG----STQKLVPFLQSV-DLP-CPMYHNPADYIIELACGEYGYDKVDT 367
            .||::.:|. .|..:|.|    ::.|::.:.|:: .:| ....:|||.:::|::
plant  1032 AFDELLLLKRGGQVIYAGPLGQNSHKIIEYFQAIHGVPKIKEKYNPATWMLEVS----------- 1085

  Fly   368 LKLATENGSCLTW---FHNPSAVLRAEVLMRKYPIPKKTKSRSLEDTSYS----NQCSVLLRRGF 425
             .:|.|....:.:   :...|...:.:.|:::...|.:..|.....|.:|    .|....|.:.:
plant  1086 -SMAAEAKLEIDFAEHYKTSSLYQQNKNLVKELSTPPQGASDLYFSTRFSQSLLGQFKSCLWKQW 1149

  Fly   426 IKAKRDTTMTHLRIGVNIAVAALFGAMYDHTG--REGSRVLDN-----YNLLFAILMHHSMTTMM 483
            |...|.......|....:|.|.:.|:::...|  ||.:..|..     |..:..:.:::|.:...
plant  1150 ITYWRTPDYNLARFFFTLAAAVMLGSIFWKVGTKRENANDLTKVIGAMYAAVLFVGVNNSSSVQP 1214

  Fly   484 LTVLTFPMDISILIKEHFNRWYSLKAYYTAMTLVDLPISIISCFFFTVIVYLWSYQPMEW--IRF 546
            |    ..::.|:..:|.....||...|..|..:.::|..:|...::|:|:|  :....||  .:|
plant  1215 L----IAVERSVFYRERAAEMYSALPYALAQVVCEIPYVLIQTTYYTLIIY--AMMCFEWTLAKF 1273

  Fly   547 FMFFSISLLTVFVGHSFGLM--------------IGAWFDVVNGTFLAPVLTIPMMMFAGFGVTL 597
            |.|:.:|.::......:|:|              .||::.:.|             :|:||.:..
plant  1274 FWFYFVSFMSFLYFTYYGMMTVALTPNQQVAAVFAGAFYGLFN-------------LFSGFVIPR 1325

  Fly   598 RDLPSYLRWGSHISYLRYGLEGFISAIYGLDRGTLACEEAP----------YC--HYRYPKKFLE 650
            ..:|.:..|...|..:.:.:.|.|.:.||....|:   :.|          |.  ||.|...|:.
plant  1326 PRIPKWWIWYYWICPVAWTVYGLIVSQYGDVEDTI---KVPGMANDPTIKWYIENHYGYDADFMI 1387

  Fly   651 EI-------TMRGDQFWNDVIALGVMILVFR 674
            .|       |:    |:..:.|.|:..|.|:
plant  1388 PIATVLVGFTL----FFAFMFAFGIRTLNFQ 1414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	160/659 (24%)
		ABCG_EPDR	102..326	CDD:213180	83/237 (35%)
		ABC2_membrane	420..623	CDD:279410	44/225 (20%)
ABCG29	NP_566543.1	PLN03140	1..1416	CDD:215599	168/681 (25%)
		ABC_trans_N	54..141	CDD:291196
		ABCG_PDR_domain1	156..402	CDD:213200
		ABC2_membrane	503..709	CDD:279410
		PDR_assoc	716..780	CDD:285559	3/7 (43%)
		ABCG_PDR_domain2	811..1049	CDD:213199	83/237 (35%)
		ABC2_membrane	1144..1351	CDD:279410	44/225 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910