DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5853 and ABCG1

DIOPT Version :9

Sequence 1:	NP_001260309.1	Gene:	CG5853 / 34322	FlyBaseID:	FBgn0032167	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_181467.1	Gene:	ABCG1 / 818520	AraportID:	AT2G39350	Length:	740	Species:	Arabidopsis thaliana

Alignment Length:	593	Identity:	147/593 - (24%)
Similarity:	272/593 - (45%)	Gaps:	59/593 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 DALNNLPAREPVDMEFKELSLTVKLGFNRGSKEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDAL 156
            |..|..|.|...|.|..:.:       ...:|.:|:|:.|:....:::|::|.||:|||||:|||
plant    83 DFRNLFPRRRTEDPEIAQTA-------RPKTKTLLNNISGETRDGEIMAVLGASGSGKSTLIDAL 140

  Fly   157 SGFKTTG-VDGSILLNGRRRDLPSFRRMSCYITQDDRLQPLLTVNENMHIAADLKLGQTVSYEEK 220
            :.....| :.|::.|||........:.:|.|:.|||.|.|:|||.|.:..||:.:|.:::...:|
plant   141 ANRIAKGSLKGTVKLNGETLQSRMLKVISAYVMQDDLLFPMLTVEETLMFAAEFRLPRSLPKSKK 205

  Fly   221 ESRIEDILLLLGLYNHDQTLT-----MRLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCT 280
            :.|::.::..||:.|..:|:.     ..:|||:::|:||.:::|::|.::||||||:||||:|..
plant   206 KLRVQALIDQLGIRNAAKTIIGDEGHRGISGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTSAF 270

  Fly   281 KVLELLKKLTSQGRTIICTIHQPTAKLFQIFDQVYVLSAGNCVYQGSTQKLVPFLQSVDLPCPMY 345
            .|:::||::...|..:|.:||||:.::..:.|::..||.|:.||.||...|..|......|.|..
plant   271 MVVKVLKRIAQSGSIVIMSIHQPSHRVLGLLDRLIFLSRGHTVYSGSPASLPRFFTEFGSPIPEN 335

  Fly   346 HNPADYIIEL-------ACGEYGY----DKVDTLKLATENGSCLTWFHNP-----------SAVL 388
            .|..::.::|       |.|..|.    .|...:|..:.....||...:|           :::.
plant   336 ENRTEFALDLIRELEGSAGGTRGLIEFNKKWQEMKKQSNRQPPLTPPSSPYPNLTLKEAIAASIS 400

  Fly   389 RAEVLMRKYPIP---KKTKSRSLEDTSYSN----QCSVLLRRGFIKAKRDTTMTHLRIGVNIAVA 446
            |.:::.....:.   ..|.:.:|...:::|    :...|.:|..:.::|...:..:||...:...
plant   401 RGKLVSGGESVAHGGATTNTTTLAVPAFANPMWIEIKTLSKRSMLNSRRQPELFGIRIASVVITG 465

  Fly   447 ALFGAMYDHTGREGSRVLDNYNLLFAILMHHSMTTMMLT----VLTFPMDISILIKEHFNRWYSL 507
            .:...::.........|.:... .||.    :|:||..|    :..|..:..|.::|.....|..
plant   466 FILATVFWRLDNSPKGVQERLG-FFAF----AMSTMFYTCADALPVFLQERYIFMRETAYNAYRR 525

  Fly   508 KAYYTAMTLVDLPISIISCFFFTVIVYLWSYQPMEWIRFFMFFSISLLTVF-VGHSF-GLMIGAW 570
            .:|..:..:|..|..|.....|....| |:......:...:|:.:.:|..| .|.|| ..:.|..
plant   526 SSYVLSHAIVSFPSLIFLSVAFAATTY-WAVGLDGGLTGLLFYCLIILASFWSGSSFVTFLSGVV 589

  Fly   571 FDVVNGTFLAPVLTIPMMMFAGFGVTLRDLPSYLRWGSHISYLRYGLEG-----FISAIYGLDRG 630
            ..|:.|..:...:....::|:||.:....:|.|..|..::|.::|..|.     |..|.....||
plant   590 PSVMLGYTIVVAILAYFLLFSGFFINRNRIPDYWIWFHYMSLVKYPYEAVLQNEFSDATKCFVRG 654

  Fly   631 TLACEEAP 638
            ....:..|
plant   655 VQIFDNTP 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	145/588 (25%)
		ABCG_EPDR	102..326	CDD:213180	77/229 (34%)
		ABC2_membrane	420..623	CDD:279410	42/213 (20%)
ABCG1	NP_181467.1	3a01204	106..739	CDD:273361	141/563 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820