DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5853 and NAP12

DIOPT Version :9

Sequence 1:	NP_001260309.1	Gene:	CG5853 / 34322	FlyBaseID:	FBgn0032167	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_001323430.1	Gene:	NAP12 / 818275	AraportID:	AT2G37010	Length:	1082	Species:	Arabidopsis thaliana

Alignment Length:	801	Identity:	190/801 - (23%)
Similarity:	336/801 - (41%)	Gaps:	216/801 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GVA---GLGLGIEIGEVTSSRVYNS--TTVPV---GNSGGWRNAQSSVTP--PPIPTPPQ----V 65
            |||   .:||..::.: |.||:.::  ...||   |.|...:...|::|.  ..:...|.    .
plant   352 GVAKNQKMGLSAQLSQ-TFSRMKSARKDATPVKASGKSKDKKKEPSNLTKMMKSMEENPSNNEGF 415

  Fly    66 NYTNGNEPSKQPPL----------------------EPVVEEE---------VHFDTDALNNLPA 99
            |...|::|.|:|..                      |..:|:.         :...||  ..:..
plant   416 NVGTGSKPGKKPQAPKGKQLHTQSQIFKYAYGQIEKEKAMEQNNKNLTFSGVISMATD--TEMRT 478

  Fly   100 REPVDMEFKELSLTVKLGFNRGS-KEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSGFKTTG 163
            |..:::.||:|:||:|     |. |.||.:|.||....::.|:||||||||:|.|.||:| |.||
plant   479 RPVIEVAFKDLTLTLK-----GKHKHILRSVTGKIMPGRVSAVMGPSGAGKTTFLSALAG-KATG 537

  Fly   164 V--DGSILLNGRRRDLPSFRRMSCYITQDDRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIED 226
            .  .|.||:|||...:.|:::::.::.|||.:...|||.||:..:|..:|...:|..:|...||.
plant   538 CTRTGLILINGRNDSINSYKKITGFVPQDDVVHGNLTVEENLRFSARCRLSAYMSKADKVLIIER 602

  Fly   227 ILLLLGLYNHDQTLT-----MRLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELL 286
            ::..|||.:...:|.     ..:||||:||:::.:|::..|:::.||||||||||:|...:|..|
plant   603 VIESLGLQHVRDSLVGTIEKRGISGGQRKRVNVGVEMVMEPSLLILDEPTTGLDSASSQLLLRAL 667

  Fly   287 KKLTSQGRTIICTIHQPTAKLFQIFDQVYVLSAGN-CVYQGSTQKLVPFLQSVDLPCPMYHNPAD 350
            ::...:|..|...:|||:..::::||.:.:|:.|. .||.||.:|:..:...:.:..|...||.|
plant   668 RREALEGVNICMVVHQPSYTMYKMFDDMIILAKGGLTVYHGSVKKIEEYFADIGITVPDRVNPPD 732

  Fly   351 YIIELACGEYGYDKVDTLKLATENGSCLTW-FHNPSAVLRAEVLMRKYPI-----------PKKT 403
            :.|::..|....|...|::...     :.| .||            .||:           |..:
plant   733 HYIDILEGIVKPDGDITIEQLP-----VRWMLHN------------GYPVPHDMLKFCDGLPSSS 780

  Fly   404 KSRSLEDTSYSNQCSVLLRRGFIKAKRDTTMTHLRIGVNIA------VAALFGAMYDH-TGREGS 461
            ...:.||:::::..:.|.:.  :|...:.|...|:...:.:      |....|..|.: .||.|.
plant   781 TGSAQEDSTHNSFSNDLWQD--VKTNVEITKDQLQHNYSNSHDNSNRVTPTVGRQYRYFVGRVGK 843

  Fly   462 RVLDNYNLL---FAILM-------------HHSMTTMMLTVLTFPMDISILIKEHFNRWYSLK-- 508
            :.|....|.   |.||:             ..::.|:..|...  :.:|:|.|....|.:|:.
plant   844 QRLREARLQALDFLILLVAGACLGTLAKVNDETIDTLGYTYTI--IAVSLLCKISALRSFSVDKL 906

  Fly   509 -------------AYYTAMTLVD------LPISIISCFFF-------------TVIVYLWSYQPM 541
                         |::.|...:|      .|:..:|.|:|             .::..::....|
plant   907 QYWRESAAGISSLAHFMAKDTMDHLNTIMKPLVYLSMFYFFNNPRSSFEDNYIVLVCLVYCVTGM 971

  Fly   542 EWIRFFMFFSIS---LLTVFVGHSFGLMIGAWFDVVNGTFLAPVLTIPMMMFAGFGVTLRDLPS- 602
            .:| |.:.:|.|   ||:|                     |.||:   |.:.|.     :|..|
plant   972 AYI-FAILYSPSAAQLLSV---------------------LVPVV---MTLIAN-----QDKESM 1006

  Fly   603 YLRWGSHISYLRYGLEGFI-------SAIYGLDRGTLACEEAPYCHYRYPKKFLEEITMRGDQFW 660
            .|::.....|.::.||.|:       |.::.:.|          |         ..::..|....
plant  1007 VLKYLGSFCYPKWTLEAFVLSNAQRYSGVWVVTR----------C---------SSLSQNGYDLS 1052

  Fly   661 NDVIALGVMI---LVFRFVSY 678
            :.::.|.|::   |:.||::|
plant  1053 DWILCLIVLVLMGLICRFIAY 1073

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	166/674 (25%)
		ABCG_EPDR	102..326	CDD:213180	87/232 (38%)
		ABC2_membrane	420..623	CDD:279410	49/270 (18%)
NAP12	NP_001323430.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820