DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5853 and ABCG7

DIOPT Version :9

Sequence 1:	NP_001260309.1	Gene:	CG5853 / 34322	FlyBaseID:	FBgn0032167	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_849922.1	Gene:	ABCG7 / 814660	AraportID:	AT2G01320	Length:	728	Species:	Arabidopsis thaliana

Alignment Length:	608	Identity:	173/608 - (28%)
Similarity:	303/608 - (49%)	Gaps:	45/608 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 PVDMEFKELSLTVKLGFNRGSKEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSGFKTTG--- 163
            ||.:.::.::.::....::..:.:|.||.|:....:|:|||||||:||:|||:.|:|..:..
plant    67 PVTIRWRNITCSLSDKSSKSVRFLLKNVSGEAKPGRLLAIMGPSGSGKTTLLNVLAGQLSLSPRL 131

  Fly   164 -VDGSILLNGRRRDLPSFRRMSCYITQDDRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIEDI 227
             :.|.:.:||:.....:::  ..::.|:|.....|||.|.:..||:|:|.:..|.||::..:.::
plant   132 HLSGLLEVNGKPSSSKAYK--LAFVRQEDLFFSQLTVRETLSFAAELQLPEISSAEERDEYVNNL 194

  Fly   228 LLLLGLYNHDQTL-----TMRLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLK 287
            ||.|||.:...:.     ...:|||:|||||:|.|||.:|:|:|.||||||||:....||:|.|:
plant   195 LLKLGLVSCADSCVGDAKVRGISGGEKKRLSLACELIASPSVIFADEPTTGLDAFQAEKVMETLQ 259

  Fly   288 KLTSQGRTIICTIHQPTAKLFQIFDQVYVLSAGNCVYQGSTQK-LVPFLQSVDLPCPMYHNPADY 351
            ||...|.|:||:||||...::..||.:.:|:.|..||.|...| .:.:..:....||.:.|||::
plant   260 KLAQDGHTVICSIHQPRGSVYAKFDDIVLLTEGTLVYAGPAGKEPLTYFGNFGFLCPEHVNPAEF 324

  Fly   352 IIELACGEYGYDKVDTLKLATENGSCL--TWFHNPSAVLRAEVLMRKYPIPKKTKSRS---LEDT 411
            :.:|.  ...|...:|:..:.:....|  .:....|:||.|..|..|.......:.|.   :|.|
plant   325 LADLI--SVDYSSSETVYSSQKRVHALVDAFSQRSSSVLYATPLSMKEETKNGMRPRRKAIVERT 387

  Fly   412 -SYSNQCSVLLRRGFIKAKRDTTMTHLRIGVNIAVAALFGAMYDHTGREGSRVLDNYNLLFAILM 475
             .:..|..:||:|.:::|.||.....:|..:::|.|.:||:::...|:..:.:.|...||....:
plant   388 DGWWRQFFLLLKRAWMQASRDGPTNKVRARMSVASAVIFGSVFWRMGKSQTSIQDRMGLLQVAAI 452

  Fly   476 HHSMTTMMLTVLTFPMDISILIKEHFNRWYSLKAYYTAMTLVDLPISIISCFFFTVIVYLWSYQP 540
            :.:|..:..||..||.:.:|:.:|.....|||..|..:.|:.::||.......|..::|     |
plant   453 NTAMAALTKTVGVFPKERAIVDRERSKGSYSLGPYLLSKTIAEIPIGAAFPLMFGAVLY-----P 512

  Fly   541 MEWI-----RFFMFFSISLLTVFVGHSFGLMIGAWFDVVNGTF-LAPVLTIPMMMFAGFGVTLRD 599
            |..:     ||..|..|..:..|...:.||.:||......... :.|.|....::|.|:.|...:
plant   513 MARLNPTLSRFGKFCGIVTVESFAASAMGLTVGAMVPSTEAAMAVGPSLMTVFIVFGGYYVNADN 577

  Fly   600 LPSYLRWGSHISYLRYGLEGF-ISAIYGL---DRGTLACEEAPYCHYRYPKKFLEEITMRGDQFW 660
            .|...||....|.:|:..:|. |:...||   .:.|...:..        ::.||.::..|.:.
plant   578 TPIIFRWIPRASLIRWAFQGLCINEFSGLKFDHQNTFDVQTG--------EQALERLSFGGRRI- 633

  Fly   661 NDVIALGVMILVFRF-VSYVVLK 682
            .:.||....||:|.: .:|::|:
plant   634 RETIAAQSRILMFWYSATYLLLE 656

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	173/608 (28%)
		ABCG_EPDR	102..326	CDD:213180	85/232 (37%)
		ABC2_membrane	420..623	CDD:279410	54/209 (26%)
ABCG7	NP_849922.1	ABCG_EPDR	67..298	CDD:213180	85/232 (37%)
		3a01204	90..655	CDD:273361	170/582 (29%)
		ABC2_membrane	397..601	CDD:279410	53/208 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.720