Protein Alignment CG5853 and abcg4b

DIOPT Version :9

• Sequence 1: NP_001260309.1
• Gene: CG5853 / 34322
• FlyBaseID: FBgn0032167
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_001104682.1
• Gene: abcg4b / 794238
• ZFINID: ZDB-GENE-080215-10
• Length: 644
• Species: Danio rerio
• Alignment Length: 640
• Identity: 270/640 - (42%)
• Similarity: 398/640 - (62%)
• Gaps: 38/640 - (5%)

  Fly    70 GNEPSKQPPLEPVVEEEVHF-DTDALNNLPAREPVDMEFKELSLTVKLG---FNRGSKEILHNVC 130
            |::|.:.|.|..:.:.|.|. :....::||.|..|::|||||..|::.|   ..:|.|.:|..:.
Zfish    23 GSQPQEAPLLTHLKKVENHITEAQRFSHLPKRTTVELEFKELCYTIREGPWWKKQGYKALLKCLS 87

  Fly   131 GKFPGSQLIAIMGPSGAGKSTLLDALSGFKTTGVDGSILLNGRRRDLPSFRRMSCYITQDDRLQP 195
            |||...:||.||||||||||||::.|:|::.||:.|.||:||:.||..:||:|||||.|:|:|.|
Zfish    88 GKFSSRELIGIMGPSGAGKSTLMNILAGYRETGMTGQILVNGKLRDPRTFRKMSCYIMQEDKLLP 152

  Fly   196 LLTVNENMHIAADLKLGQTVSYEEKESRIEDILLLLGLYNHDQTLTMRLSGGQKKRLSIAMELIN 260
            .|:|.|.|.::|:|||.:  |.|.|:..|::||..|||:....|.|:.|||||.|||:||:||:|
Zfish   153 HLSVQEAMMVSANLKLNE--SSEVKKELIKEILTALGLHECVHTRTVSLSGGQCKRLAIALELVN 215

  Fly   261 NPTVMFLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQPTAKLFQIFDQVYVLSAGNCVYQ 325
            ||.|||.||||:||||:||.:|:.|:|.|...|||||||||||:||||::||::|:||.|.|:|:
Zfish   216 NPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIYK 280

  Fly   326 GSTQKLVPFLQSVDLPCPMYHNPADYIIELACGEYGYDKVDTLKLATENGSCLTWFHNPSAVLRA 390
            ||...|:|:|:.:.|.||.||||||:|||:|.|||| |....|..|.:.|.|
Zfish   281 GSVPYLIPYLRGLGLHCPTYHNPADFIIEVASGEYG-DLNPVLFEAVQGGMC------------- 331

  Fly   391 EVLMRKYPIPKKT-----KSRSLED----------TSYSNQCSVLLRRGFIKAKRDTTMTHLRIG 440
             .|..|.....||     .::.::|          ||...|..:|.:|.||...||..:||||:.
Zfish   332 -ALEEKCNCIDKTTVTSCAAKCVKDPGHVESHTFATSSLTQFCILFKRTFITICRDQVLTHLRLM 395

  Fly   441 VNIAVAALFGAMYDHTGREGSRVLDNYNLLFAILMHHSMTTMMLTVLTFPMDISILIKEHFNRWY 505
            .:|::..|.|.:|.:.|.:.|:|.:|...||..::......:|.||||||:::::.::||.|.||
Zfish   396 SHISIGVLIGLLYLNIGNDASKVFNNTGFLFFSMLFLMFGALMPTVLTFPLEMAVFLREHLNYWY 460

  Fly   506 SLKAYYTAMTLVDLPISIISCFFFTVIVYLWSYQPMEWIRFFMFFSISLLTVFVGHSFGLMIGAW 570
            ||||||.|.|:.|:|..::....:..|||..:.||.|..|:.:|.::|:.|..|..|.||::||.
Zfish   461 SLKAYYLAKTMADIPFQVLCPIMYCSIVYWMTEQPPEASRYLLFLALSICTALVAQSLGLLVGAA 525

  Fly   571 FDVVN-GTFLAPVLTIPMMMFAGFGVTLRDLPSYLRWGSHISYLRYGLEGFISAIYGLDRGTLAC 634
            ...:. .||:.||..||:::|:||.|....:|.||:|.|::||:|||.|..|.:|||::|....|
Zfish   526 STSLQVATFVGPVTGIPVLLFSGFFVNFDTIPEYLQWSSYVSYVRYGFEEVILSIYGMNRTEREC 590

  Fly   635 EEAPYCHYRYPKKFLEEITMRGDQFWNDVIALGVMILVFRFVSYVVLKAKIKSIR 689
             ....|.::.|::.|:.:.:...:.:.|.|.||:..::.|..:||||:.||||.|
Zfish   591 -PGRVCKFQRPEEVLQLLDVEDAKLYMDFIVLGIFFVILRLATYVVLRYKIKSER 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	263/610 (43%)
		ABCG_EPDR	102..326	CDD:213180	124/226 (55%)
		ABC2_membrane	420..623	CDD:279410	80/203 (39%)
abcg4b	NP_001104682.1	3a01204	42..644	CDD:273361	263/619 (42%)
		ABCG_EPDR	57..281	CDD:213180	124/225 (55%)
		ABC2_membrane	375..574	CDD:279410	78/198 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	131	1.000	Domainoid score	I5116
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177791at33208
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	1	1.000	-	-		otm25175
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R138
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.810