Protein Alignment CG5853 and abcg4a

DIOPT Version :10

• Sequence 1: NP_788019.1
• Gene: CG5853 / 34322
• FlyBaseID: FBgn0032167
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: XP_687685.2
• Gene: abcg4a / 564842
• ZFINID: ZDB-GENE-050517-39
• Length: 641
• Species: Danio rerio
• Alignment Length: 656
• Identity: 280/656 - (42%)
• Similarity: 404/656 - (61%)
• Gaps: 32/656 - (4%)

  Fly    50 AQSSVTPPPIPTPPQVNYTNGNEPSKQPPLEPVVEEEVHF-DTDALNNLPAREPVDMEFKELSLT 113
            |:.::.|..:..|.:.....|.:.:....|:.|   |.|. :....::||.|..||:||.|||.|
Zfish     2 AEKTLEPGSVSIPMEETKRAGGDAAMLTHLKKV---ENHITEAQRFSHLPRRSTVDLEFTELSYT 63

  Fly   114 VKLG---FNRGSKEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSGFKTTGVDGSILLNGRRR 175
            ::.|   ..||.|.:|..:.|||...:||.||||||||||||::.|:|::.||:.|.||:|||.|
Zfish    64 IREGPCWRRRGFKALLKCLSGKFCSRELIGIMGPSGAGKSTLMNILAGYRETGMKGQILVNGRPR 128

  Fly   176 DLPSFRRMSCYITQDDRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIEDILLLLGLYNHDQTL 240
            ||.:||:|||||.|||.|.|.||..|.|.::|:|||.:.:  |.|:..:.:||..|||....||.
Zfish   129 DLRTFRKMSCYIMQDDMLLPHLTTREAMMVSANLKLNENM--EVKKELVNEILTALGLQECAQTR 191

  Fly   241 TMRLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQPTA 305
            |:.|||||.|||:||:||:|||.|||.||||:||||:||.:|:.|:|.|...|||||||||||:|
Zfish   192 TISLSGGQCKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSA 256

  Fly   306 KLFQIFDQVYVLSAGNCVYQGSTQKLVPFLQSVDLPCPMYHNPADYIIELACGEYGYDKVDTLKL 370
            |||::||::|:||.|.|:|:|:...|:|:|:::.|.||.||||||:|||:|.|||| |....|..
Zfish   257 KLFEMFDKLYILSQGQCIYKGTVPYLIPYLKNLGLHCPTYHNPADFIIEVASGEYG-DLNPVLFE 320

  Fly   371 ATENGSC-------LTWFHNPSAVLRAEVLMRKYP----IPKKTKSRSLEDTSYSNQCSVLLRRG 424
            |.:.|.|       .:..::|:....::.    ||    |.|.|.:     ||...|..:|.:|.
Zfish   321 AVQGGLCSDDSKKNSSDKNDPTTSCPSQC----YPDSGYIEKHTFA-----TSTLTQFCILFKRT 376

  Fly   425 FIKAKRDTTMTHLRIGVNIAVAALFGAMYDHTGREGSRVLDNYNLLFAILMHHSMTTMMLTVLTF 489
            ||...||..:||||:..::.:..|.|.:|.:.|.:.|:|.:|...||..::......:|.|||||
Zfish   377 FITICRDVVLTHLRVMSHLCIGVLIGLLYLNIGNDASKVFNNTGFLFFSMLFLMFAALMPTVLTF 441

  Fly   490 PMDISILIKEHFNRWYSLKAYYTAMTLVDLPISIISCFFFTVIVYLWSYQPMEWIRFFMFFSISL 554
            |:::.:.|:||.|.||||||||.|.|:.|:|..:|....:..|||..:.||.|..|:.:|.::|.
Zfish   442 PLEMGVFIREHLNYWYSLKAYYLAKTMADIPFQVICPIMYCSIVYWMTEQPPEAGRYLLFMALST 506

  Fly   555 LTVFVGHSFGLMIGAWFDVVN-GTFLAPVLTIPMMMFAGFGVTLRDLPSYLRWGSHISYLRYGLE 618
            .|..|..|.||:|||....:. .||:.||..||:::|:||.|....:|.||:|.|::||:|||.|
Zfish   507 STALVAQSLGLLIGAASTSLQVATFVGPVSAIPVLLFSGFFVNFDTIPKYLQWSSYVSYVRYGFE 571

  Fly   619 GFISAIYGLDRGTLACEEAPYCHYRYPKKFLEEITMRGDQFWNDVIALGVMILVFRFVSYVVLKA 683
            |.|.:|||::|..|.| ....|.::.|::.|:.:.:...:.:.|.:.|||..||.|..:|.||:.
Zfish   572 GVILSIYGMNRSELEC-PGIVCKFQKPEEVLQLLDVEDAKLYVDFMVLGVFFLVLRLATYFVLRY 635

  Fly   684 KIKSIR 689
            |:||.|
Zfish   636 KVKSER 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_788019.1	3a01204	97..689	CDD:273361	271/606 (45%)
abcg4a	XP_687685.2	3a01204	38..641	CDD:273361	271/615 (44%)