Protein Alignment CG5853 and abcg5

DIOPT Version :9

• Sequence 1: NP_001260309.1
• Gene: CG5853 / 34322
• FlyBaseID: FBgn0032167
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_001122162.1
• Gene: abcg5 / 557317
• ZFINID: ZDB-GENE-050517-40
• Length: 652
• Species: Danio rerio
• Alignment Length: 574
• Identity: 166/574 - (28%)
• Similarity: 272/574 - (47%)
• Gaps: 62/574 - (10%)

  Fly   122 SKEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSG--FKTTGVDGSILLNGRRRDLPSFRRMS 184
            :::||:.|.......|::.|:|.||:||:|||||::|  ..:..:.|.:.:|||:.....|:...
Zfish    69 TRQILNEVSFHLDSGQIMGILGNSGSGKTTLLDAIAGRIGNSGNLQGEVFVNGRKLKREQFQDCF 133

  Fly   185 CYITQDDRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIEDIL--LLLGLYNHD---QTLTMRL 244
            .|:.|.|.|...|||.|.:...|.|.| :..|.|....::..::  |.||...|.   ..:...:
Zfish   134 SYVLQSDNLLSYLTVEETLTYTAQLAL-RKHSAEAIRKKVTAVMAELSLGHVAHSVIGGRVFPGI 197

  Fly   245 SGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQPTAKLFQ 309
            |||:::|:|||.:|:.:|.|:.||||||||||.:..:::.||.:|..:.|.:|.|||||.::||:
Zfish   198 SGGERRRVSIASQLLQDPKVILLDEPTTGLDSMTANQIVMLLAELARRDRIVIVTIHQPRSELFR 262

  Fly   310 IFDQVYVLSAGNCVYQGSTQKLVPFLQSVDLPCPMYHNPADYIIELA-----CGE---YGYDKVD 366
            ||:::.::|.|..|:.|...|:|.|..|....||.|.||.|..::|.     |.|   ..|.::.
Zfish   263 IFNRIAIMSQGELVFCGEPHKMVDFFSSCGYECPEYCNPFDIYVDLTSVDTRCSEREAATYRRMH 327

  Fly   367 TLKLATENGSCLTWFHNPSAVLRAEVLMRKYP-IPKKTKSRSLEDTSYSNQCSVLLRRGFIKAKR 430
            .:..|.:|....|   |....:.........| ||.|:|    |..:..::..|||||.|....|
Zfish   328 DITSAYQNSEIYT---NMQEKIEQSCQRPDKPMIPFKSK----ESPNCISKLGVLLRRTFRNVSR 385

  Fly   431 DTTMTHLRIGVNIAVAALFGAMYDHTGREGSR--VLDNYNLLFAILMHHSMTTMMLTVLTFPMDI 493
            |.....:|:..|:.............|::.::  |.|...|::..:.....|.|:..|..||...
Zfish   386 DRMGILMRLSQNLIYGLFIAFFLMRLGKDVTKGAVQDRIGLIYQSMGASPYTGMLNAVALFPALR 450

  Fly   494 SILIKEH----FNRWYSLKAYYTAMTLVDLPISIISCFFFTVIVYLWS--YQPMEWIRFFMFFSI 552
            :|..:|.    :.:|....||...:    ||.||||.|.|...:| |:  ..| :.:||..|.::
Zfish   451 AISDQESKDGLYQKWQMFLAYIIHI----LPFSIISVFIFASFLY-WTVGMNP-DPVRFLCFSAV 509

  Fly   553 SLLTVFVGHSFGL-MIGAWFD---VVNGTFLAPVLTIPMMMFAGFGVTLRDLPSYLRWGSHISYL 613
            .::...:|....| ::|...|   |.:|..|..:..|  |:.:||....:.:|...:|.|::::.
Zfish   510 VMVPHIIGELLTLVLLGVVQDPNMVNSGVALLNIAGI--MVGSGFLRGFKQMPVVFQWLSYLTFQ 572

  Fly   614 RYGLEGFI-SAIYGL----------------DRGTLACEEA-PYCHYRYPKKFL 649
            :||.|..| :..|||                |.|.:..::. |....||.:.||
Zfish   573 KYGCELLIVTEFYGLNFTCTPIAGLPGECLVDSGNMIIDQGYPGALSRYTQDFL 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	166/574 (29%)
		ABCG_EPDR	102..326	CDD:213180	75/210 (36%)
		ABC2_membrane	420..623	CDD:279410	55/215 (26%)
abcg5	NP_001122162.1	3a01204	50..645	CDD:273361	166/574 (29%)
		ABCG_White	53..279	CDD:213201	75/210 (36%)
		ABC2_membrane	375..582	CDD:279410	55/214 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820