DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5853 and Abcg3

DIOPT Version :9

Sequence 1:	NP_001260309.1	Gene:	CG5853 / 34322	FlyBaseID:	FBgn0032167	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	XP_038948191.1	Gene:	Abcg3 / 498327	RGDID:	1565568	Length:	703	Species:	Rattus norvegicus

Alignment Length:	723	Identity:	184/723 - (25%)
Similarity:	317/723 - (43%)	Gaps:	110/723 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 NSTTVPVGNSGGWRNAQSSVTPPPIPTPPQVNYTNGNEPSKQPPL------EPVV---EEEVHFD 90
            :.|::|      |:...|:.......|...:..|..| |.|:.||      :|:|   .|..|.|
  Rat     7 SKTSIP------WKGVSSNCVSIHRSTYKNIKPTLIN-PLKEEPLKMSSNNDPIVIPMAERRHSD 64

  Fly    91 TDALNNLP----AREPVDMEFKELSL--TVKLGFNRGSK----EILHNVCGKFPGSQLIAIMGPS 145
            ....|...    .:|.| :.|..:|.  ||:.||....:    |.|.::.| ..|..|.|||||.
  Rat    65 LPETNTSDPETLTKEAV-LSFHNISYRETVQSGFPLRQQTRVIERLSSISG-IMGPGLNAIMGPQ 127

  Fly   146 GAGKSTLLDALSGFK-TTGVDGSILLNGRRRDLPSFRRMSCYITQDDRLQPLLTVNENMHIAADL 209
            ...:|.|||.|:..: .:|:.|.||:||:.|. .:|:..|.|:.|:|.:...:||.:|:..:|.|
  Rat   128 DGSRSLLLDVLAARRDPSGLSGDILVNGKPRP-ANFKCTSGYVPQNDVVMHTVTVRDNLEFSAAL 191

  Fly   210 KLGQTVSYEEKESRIEDILLLLGLYNHDQTLTMRLSGGQKKRLSIAMELINNPTVMFLDEPTTGL 274
            :|..|::.:||..||.::|.||.| :.:|....| |...:||.|||:|||....::|||:|||.|
  Rat   192 RLPMTITRDEKRRRINEVLELLHL-DKEQNTKPR-SKELRKRTSIAVELIAEHPILFLDDPTTDL 254

  Fly   275 DSSSCTKVLELLKKLTSQGRTIICTIHQPTAKLFQIFDQVYVLSAGNCVYQGSTQKLVPFLQSVD 339
            |.::.|.|:.:|::::.:|:|||.:|:||...:|:.||.:.::::|..::.|..:..:.:..|..
  Rat   255 DLTTTTYVISVLRRMSMKGKTIIFSINQPQYSIFRFFDSLTLVASGKLMFHGPARDALEYFTSAG 319

  Fly   340 LPCPMYHNPADYIIELACGEYGYDKVDTLKLATENGSCLTWFHNPSAVLRAEVLMRKYPIPKK-- 402
            .....::||||:.:::..|                |.|.|......|....|:..|||...||
  Rat   320 YQYESHNNPADFFLDVING----------------GLCDTEEDGHEAGNYEELFERKYQATKKLA 368

  Fly   403 ---TKSRSLED-------------------------TSYSNQCSVLLRRGFIKAKRDTTMTHLRI 439
               .:||...|                         |.:.:|...:..:.|...:....:|..:.
  Rat   369 NMYAQSRLHSDTRARLDQLLGQQQLDRNSAVETTCVTPFWHQLMWITYQSFKNIRGFLLVTAKQA 433

  Fly   440 GVNIAVAALFGAMYDHTGREGSRVLDNYNLLFAILMHHSMTTMMLTVLTFPMDISILIKEHFNRW 504
            .:...:|||.|..:.........|.....||:.:.:...:|::....| |.:|....:.||.:.:
  Rat   434 VITATLAALVGIAFQILKNGCIEVYIRAGLLYLLTIFQCITSVSAGEL-FVIDRDRFLHEHTSGY 497

  Fly   505 YSLKAYYTAMTLVDL--------PISIISCFFFTVIVYLWSYQPMEWIRFFMFFSISLLTVFVGH 561
            |.:.:|:....|.:|        .|.:|:.|...|...:.|:       |.|.|::.:| .:...
  Rat   498 YRVSSYFFGKLLAELIPRRLLPSTIVLITYFIAGVKTSMSSF-------FAMLFTVMML-AYSAS 554

  Fly   562 SFGLMIGAWFDVVN-GTFLAPVLTIPMMMFAGFGVTLRDLPSYLRWGSHISYLRYGLEGFISAIY 625
            |..|.|||..:.|. .|....:..:.|:.|:|..:....|...|.|   |.|......||.:.::
  Rat   555 SLPLSIGAGENAVAVPTLFVTIYFVFMLFFSGLSLYSGSLLPQLSW---IQYFNIPHYGFKALLH 616

  Fly   626 GLDRGTLAC-----EEAPYCHYRYPKKFLEEITMRGDQ-----FWNDVIALGVMILVFRFVSYVV 680
            ....|...|     ||...||........|.:|::|..     ||.:.:||..::::...::||.
  Rat   617 NEFLGQNFCSEHNIEEVSRCHNYVICTGEEFLTIQGIDLSSWGFWENHLALACIMIILLTITYVQ 681

  Fly   681 LKAKIKSI 688
            | .::|::
  Rat   682 L-LQVKTL 688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	167/652 (26%)
		ABCG_EPDR	102..326	CDD:213180	82/230 (36%)
		ABC2_membrane	420..623	CDD:279410	45/211 (21%)
Abcg3	XP_038948191.1	3a01204	109..683	CDD:273361	157/606 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010