DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5853 and Atet

DIOPT Version :9

Sequence 1:	NP_001260309.1	Gene:	CG5853 / 34322	FlyBaseID:	FBgn0032167	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster

Alignment Length:	789	Identity:	303/789 - (38%)
Similarity:	422/789 - (53%)	Gaps:	130/789 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 TSSRVYNST-TVPVGNSGGWRNAQSSVTPPPIPTPPQV---------------NYTNGNEPSKQP 77
            ||..:..|| :...||.....||.::....|:|...|:               |..||...|...
  Fly    46 TSGNMSLSTLSTGSGNPNPNPNASTNSRQEPVPLLSQLKLTNDLKQNSHGSQNNLCNGGLGSNNH 110

  Fly    78 PLEPVVEEE-------VHFDTDALNNLPAREPVDMEFKELSLTVKLGFNRGSKEILHNVCGKFPG 135
            .|.|.|...       ....|.||::||.|.|||:||.::|.:|.....||.|.||.:|.|||..
  Fly   111 ALAPKVANNSGGSPNGQKKGTIALSHLPQRPPVDIEFCDISYSVTDSHRRGFKTILKSVSGKFRN 175

  Fly   136 SQLIAIMGPSGAGKSTLLDALSGFKTTGVDGSILLNGRRRDLPSFRRMSCYITQDDRLQPLLTVN 200
            .::.|||||||||||||::.|:|:||..:.||:|:|.:.|:|..||::||||.|||.|...|||.
  Fly   176 GEITAIMGPSGAGKSTLMNILAGYKTAQLSGSVLINSKERNLRRFRKLSCYIMQDDVLIANLTVR 240

  Fly   201 ENMHIAADLKLGQTVSYEEKESRIEDILLLLGLYNHDQTLTMRLSGGQKKRLSIAMELINNPTVM 265
            |.|.:||:||||:.:....|...:|:||..:||.....|||..|||||:||||||:||:|||.||
  Fly   241 EAMMVAANLKLGKNMISYAKVVVVEEILETIGLKESVNTLTCNLSGGQRKRLSIALELVNNPPVM 305

  Fly   266 FLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQPTAKLFQIFDQVYVLSAGNCVYQGSTQK 330
            |.||||:|||||:|.:::.||:.|...||||:||||||:|:||:.||.:|:|:.|.|||:|..:.
  Fly   306 FFDEPTSGLDSSTCFQLISLLRSLARGGRTIVCTIHQPSARLFEKFDHLYLLAQGQCVYEGRVKG 370

  Fly   331 LVPFLQSVDLPCPMYHNPADYIIELACGEYGYDKVDTLKLATENGSCLTWFH------------- 382
            |||:|.|:...||.|||||||::|:|.|||| |.|..|..|.::|:|..:.|
  Fly   371 LVPYLSSLGYECPSYHNPADYVLEVASGEYG-DAVPKLVDAVKSGACKKYAHKDYVLTLAQKGCN 434

  Fly   383 ------------NPSAVLRAE---------VLMRKYPI--PKKTKSRSLE-DTSYSNQCSV---- 419
                        |..|:|..|         .|....|:  |.:.|...|| ..|.::.|||
  Fly   435 NDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKPPKLETQQSQNSDCSVVNMP 499

  Fly   420 ----------------------------------------------------------------L 420
                                                                            |
  Fly   500 TNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLPNKTGFPTSGWTQFWIL 564

  Fly   421 LRRGFIKAKRDTTMTHLRIGVNIAVAALFGAMYDHTGREGSRVLDNYNLLFAILMHHSMTTMMLT 485
            |:|.|....||..:||:|:..::.|.|:.|.:|...|.|.|:::.|...:|.:.:..:.|.||.|
  Fly   565 LKRSFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVGNEASKIMSNAGCIFFVSLFTTFTAMMPT 629

  Fly   486 VLTFPMDISILIKEHFNRWYSLKAYYTAMTLVDLPISIISCFFFTVIVYLWSYQPMEWIRFFMFF 550
            :||||.::|:.::||.|.||||||:|.|.|:.|:|..|:....:.::||..:.||||..|..||.
  Fly   630 ILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYVLVVYYLTSQPMELERVSMFV 694

  Fly   551 SISLLTVFVGHSFGLMIGAWFDVVNGTFLAPVLTIPMMMFAGFGVTLRDLPSYLRWGSHISYLRY 615
            .|.:|...|..|.||:|||..::..|.||.||.|||.::|:||.|....:|.||:|.:::||:||
  Fly   695 LICVLNSLVAQSLGLLIGAGMNIETGVFLGPVTTIPTILFSGFFVNFDTIPGYLQWVTYVSYVRY 759

  Fly   616 GLEGFISAIYGLDRGTLACEEAPYCHYRYPKKFLEEITMRGDQFWNDVIALGVMILVFRFVSYVV 680
            |.||.:.||||:||..:.|.:. |||||.|||||||::|....||.|.:||..:....|.::|.|
  Fly   760 GFEGAMVAIYGMDRAKMQCNQM-YCHYRVPKKFLEEMSMDNALFWVDAVALIGIFFALRIIAYFV 823

  Fly   681 LKAKIKSIR 689
            |:.|:..||
  Fly   824 LRWKLHMIR 832

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	280/696 (40%)
		ABCG_EPDR	102..326	CDD:213180	122/223 (55%)
		ABC2_membrane	420..623	CDD:279410	83/202 (41%)
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	278/689 (40%)
		ABCG_EPDR	142..366	CDD:213180	122/223 (55%)
		ABC2_membrane	564..767	CDD:279410	83/202 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28143
OrthoDB	1	1.010	-	-		D177791at33208
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	1	1.000	-	-		otm25175
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	1	1.100	-	-	P	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
	10	9.830