DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5853 and Abca6

DIOPT Version :9

Sequence 1:	NP_001260309.1	Gene:	CG5853 / 34322	FlyBaseID:	FBgn0032167	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	XP_006247716.1	Gene:	Abca6 / 303639	RGDID:	1308998	Length:	1630	Species:	Rattus norvegicus

Alignment Length:	371	Identity:	97/371 - (26%)
Similarity:	160/371 - (43%)	Gaps:	94/371 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 TNGNEPSKQPPLEPVVEEEVHFDTDALNNLPAREPVDMEFKELSLTVKLGFNRGSKEI-LHNVCG 131
            |:.|:.::: .::|.:..:.:|           ||||.|:            :|.:.| :.|:..
  Rat   449 TSRNKVTER-DIDPELPSDEYF-----------EPVDPEY------------QGKEAIRIRNIRK 489

  Fly   132 KFPG-----------------SQLIAIMGPSGAGKSTLLDALSGFK--TTGVDGSILLN---GRR 174
            ::.|                 ||:.|::|..|||||:||:.|:|..  |:|:  :.:.|   ...
  Rat   490 EYKGKSGKVEALKGLFFDVYESQITAVLGHGGAGKSSLLNILNGLSVPTSGL--ATVYNKNLSEM 552

  Fly   175 RDLPSFRRMSCYITQDDRLQPLLTVNENMHIAADLK--LGQTVSYEEKESRIEDILLLLGLYNHD 237
            :||...|:|.....|.:.....|||.||:.:.|::|  :.|:|:.|     ::.||..|.:....
  Rat   553 QDLKEIRKMIGVCPQHNVQFDALTVKENLTLFANIKGIVPQSVAQE-----VQQILSELDMQTIQ 612

  Fly   238 QTLTMRLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQ 302
            ..|...||.|||::|:..:.::.:|.::.|||||.|||..|..:|...||:..:....:..|  |
  Rat   613 DELAEHLSEGQKRKLTFGVAILGDPRILLLDEPTAGLDPFSRQRVWGFLKERRADRVILFST--Q 675

  Fly   303 PTAKLFQIFDQVYVLSAGNCVYQGSTQKLVPFLQSVDLPCPM---YHNPADYIIELACGEYGYDK 364
            .|.:...:.|:..:||.|.....||         ||.|....   ||      :.|...|
  Rat   676 FTDEADILADRKVILSNGALKCTGS---------SVFLKRKWGLGYH------LSLFMNE----- 720

  Fly   365 VDTLKLATENGSCLTWF---HNPSAVLRA---EVLMRKYPIPKKTK 404
                   |.:...||.|   |.|.|.|:|   |.|:...|:.|.:|
  Rat   721 -------TCDSEQLTSFINHHIPGAKLKAKTKEKLVYTLPLEKTSK 759

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	93/342 (27%)
		ABCG_EPDR	102..326	CDD:213180	69/248 (28%)
		ABC2_membrane	420..623	CDD:279410
Abca6	XP_006247716.1	ABC2_membrane_3	35..420	CDD:289468
		ABC2_membrane_4	220..409	CDD:289500
		CcmA	480..795	CDD:224054	87/316 (28%)
		ABC_subfamily_A	482..705	CDD:213230	68/240 (28%)
		ABC2_membrane_3	859..1171	CDD:289468
		ABC2_membrane_4	1007..1178	CDD:289500
		CcmA	1279..1605	CDD:224054
		ABC_subfamily_A	1300..1514	CDD:213230
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000