Protein Alignment CG5853 and Abcg2

DIOPT Version :9

• Sequence 1: NP_001260309.1
• Gene: CG5853 / 34322
• FlyBaseID: FBgn0032167
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_001342406.1
• Gene: Abcg2 / 26357
• MGIID: 1347061
• Length: 657
• Species: Mus musculus
• Alignment Length: 622
• Identity: 190/622 - (30%)
• Similarity: 309/622 - (49%)
• Gaps: 53/622 - (8%)

  Fly   105 MEFKELSLTVKL--GF---NRGSKEILHNVCGKF-PGSQLIAIMGPSGAGKSTLLDALSGFK-TT 162
            :.|..::..||:  ||   ....||||.::.|.. ||  |.||:||:|.|||:|||.|:..| ..
Mouse    37 LSFHHITYRVKVKSGFLVRKTVEKEILSDINGIMKPG--LNAILGPTGGGKSSLLDVLAARKDPK 99

  Fly   163 GVDGSILLNGRRRDLPS-FRRMSCYITQDDRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIED 226
            |:.|.:|:||..:  |: |:..|.|:.|||.:...|||.||:..:|.|:|..|:...||..||..
Mouse   100 GLSGDVLINGAPQ--PAHFKCCSGYVVQDDVVMGTLTVRENLQFSAALRLPTTMKNHEKNERINT 162

  Fly   227 ILLLLGLY----NHDQTLTMR-LSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELL 286
            |:..|||.    :...|..:| :|||::||.||.||||.:|:::||||||||||||:...||.||
Mouse   163 IIKELGLEKVADSKVGTQFIRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLL 227

  Fly   287 KKLTSQGRTIICTIHQPTAKLFQIFDQVYVLSAGNCVYQGSTQKLVPFLQSVDLPCPMYHNPADY 351
            |:::.||||||.:||||...:|::||.:.:|::|..|:.|..||.:.:..|....|..|:||||:
Mouse   228 KRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLVFHGPAQKALEYFASAGYHCEPYNNPADF 292

  Fly   352 IIELACGE-----YGYDKVDTLKLATENGS--------CLTWFHNPSAV---LRAEVLMRKYPIP 400
            .:::..|:     ...::.|.....||..|        .|:.|:..||:   .:||:........
Mouse   293 FLDVINGDSSAVMLNREEQDNEANKTEEPSKGEKPVIENLSEFYINSAIYGETKAELDQLPGAQE 357

  Fly   401 KKTKSRSLED---TSYSNQCSVLLRRGFIKAKRDTTMTHLRIGVNIAVAALFGAMYDHTGREGSR 462
            ||..|...|.   ||:.:|...:.||.|.....:...:..::.|.:.:..:.||:|.....:.:.
Mouse   358 KKGTSAFKEPVYVTSFCHQLRWIARRSFKNLLGNPQASVAQLIVTVILGLIIGAIYFDLKYDAAG 422

  Fly   463 VLDNYNLLFAILMHHSMTTMMLTVLTFPMDISILIKEHFNRWYSLKAYYTAMTLVD-LPISIISC 526
            :.:...:||.:..:...:::....| |.::..:.|.|:.:.:|.:.:|:....:.| ||:..:..
Mouse   423 MQNRAGVLFFLTTNQCFSSVSAVEL-FVVEKKLFIHEYISGYYRVSSYFFGKVMSDLLPMRFLPS 486

  Fly   527 FFFTVIVYLWSYQPMEWIRFFMFFSISLLTVFVGHSFGLMIGAWFDVVN-GTFLAPVLTIPMMMF 590
            ..||.|:|...........||:.....::..:...|..|.|.....||: .|.|..:..:.||:|
Mouse   487 VIFTCILYFMLGLKKTVDAFFIMMFTLIMVAYTASSMALAIATGQSVVSVATLLMTIAFVFMMLF 551

  Fly   591 AGFGVTLRDLPSYLRWGSHISYLRYGLEGFISAIYGLDRGTLAC-----EEAPYCHYRYP----K 646
            :|..|.||.:..:|.|..:.|..||   ||.:..|....|...|     .:...|...|.    .
Mouse   552 SGLLVNLRTIGPWLSWLQYFSIPRY---GFTALQYNEFLGQEFCPGFNVTDNSTCVNSYAICTGN 613

  Fly   647 KFL--EEITMRGDQFWNDVIALGVMILVFRFVSYVVL 681
            ::|  :.|.:.....|.:.:||..||::|..::|:.|
Mouse   614 EYLINQGIELSPWGLWKNHVALACMIIIFLTIAYLKL 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	190/622 (31%)
		ABCG_EPDR	102..326	CDD:213180	102/233 (44%)
		ABC2_membrane	420..623	CDD:279410	45/204 (22%)
Abcg2	NP_001342406.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24
		3a01204	46..651	CDD:273361	189/613 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R138
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.750