Protein Alignment CG5853 and pdr1

DIOPT Version :9

• Sequence 1: NP_001260309.1
• Gene: CG5853 / 34322
• FlyBaseID: FBgn0032167
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_593995.1
• Gene: pdr1 / 2543363
• PomBaseID: SPAPB24D3.09c
• Length: 1396
• Species: Schizosaccharomyces pombe
• Alignment Length: 616
• Identity: 157/616 - (25%)
• Similarity: 274/616 - (44%)
• Gaps: 82/616 - (13%)

  Fly    72 EPSKQPPLEPVVEEEVHFDTDALNNLPAREPVDMEFKELSLTVKLGFNRGSKEILHNVCGKFPGS 136
            ||..:||.:   .|..:...|....|...:.:.:.:::|:.||..  ....|:||.||.|....:
pombe   728 EPQDKPPSQ---TEPDNKKVDVSTTLSTNDNLVLCWRDLNFTVVT--KTSKKQILTNVSGYLKKN 787

  Fly   137 QLIAIMGPSGAGKSTLLDALSGFKTTG-VDGSILLNGRRRDLPSFRRMSCYITQDDRLQPLL--- 197
            .|.|::|.:.:|||.||..||.....| |:|.|.|:|.:.. .:.|:...|:    |..||.
pombe   788 TLTALLGENKSGKSVLLRILSQRGIAGSVEGEITLSGLKNP-KNLRKRIGYV----RKNPLFISE 847

  Fly   198 -TVNENMHIAADLKLGQTVSYEEKESRIEDILLLLGLYNHDQTLTMRLSGG----QKKRLSIAME 257
             ||.|.:.:.|.|:..:..|..|:.:.:|.::..|||......:...:..|    .|:.||||:|
pombe   848 YTVRETLRLHAALRQSKQRSLSEQYAYVEYVIDFLGLGEVADFIVGDMGKGLSLYHKRLLSIAVE 912

  Fly   258 LINNP-TVMFLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQPTAKLFQIFDQVYVLSA-G 320
            |...| :::.||||..||||.|...::.:|:||...|.:|:|::.||::::.::||.:.:|.. |
pombe   913 LSARPGSILLLDEPANGLDSQSAWMLVCILQKLARSGLSILCSVSQPSSRILELFDMMLILDLNG 977

  Fly   321 NCVYQGS----TQKLVPFLQSVDLPCPMYHNPADYIIE----LACG-EYGY----DKVDTLKLAT 372
            |.||..:    ..|||.:.:.:........:.||:::.    |..| |:.|    ...:|.|...
pombe   978 NTVYYDTMGRDLSKLVNYFKRIHGTNEHSKDTADFVLHCIQFLKQGPEFDYAGAWASTNTHKQII 1042

  Fly   373 ENGSCLTWFHNPSAVLRAEVLMRKYPIPKKTKSRSLEDTSYSNQCSVLLRRGFIKAKRDTTMTHL 437
            |:.:.:  ..||.        :.....|.:|:..    ||:..|...:..|.|:...||:::...
pombe  1043 EHVNFI--MDNPE--------LTDDDFPNETRFM----TSFFFQIYKISMRNFVAYWRDSSLLRA 1093

  Fly   438 RIGVNIAVAALFG-AMYDHTGREGSRVLDNYNLLFAILMHHSMTTMMLTVLTFPMDISILIKEHF 501
            |:..||....:.| :.|    ::|..|.:..|.:|:..|   :|....:.:.......|..:..:
pombe  1094 RVAFNIVAGLIIGFSFY----KQGVGVEETQNKMFSAYM---LTVASTSTMNGLQPKFIYFRSIY 1151

  Fly   502 NRW------YSLKAYYTAMTLVDLPISIISCFFFTVIVYLWSYQPMEW------IRFFMFFSISL 554
            .::      ||..|:..|..||:   ::|:|.|.|:..:.| |.|..:      |.|:..|:..:
pombe  1152 EQYEQNTAIYSRTAFIIAFFLVE---AVINCCFATLFFFGW-YYPSGFYEFNHNIPFYGGFAWLM 1212

  Fly   555 LTVFVGHSFGLMIG-AWFDVVNGTFLAPVLTIPMMMFAGFGVTLRDLP----SYLRWGSHISYLR 614
            |.:|..:...|.|| |......||  |.:::....:|..:...:..||    .:.:|...:|..:
pombe  1213 LMIFTLYYTTLGIGIATISPSIGT--ASIISGTAFVFIQYFNGMIQLPGVIVGFWKWMDALSPYK 1275

  Fly   615 YGLEGFISAIYGLDRGTLACEEAPYCHYRYP 645
            |.|||.|..:  |....:.||:.. .||..|
pombe  1276 YFLEGMIGGV--LHDAPITCEKFE-IHYVDP 1303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	151/591 (26%)
		ABCG_EPDR	102..326	CDD:213180	74/234 (32%)
		ABC2_membrane	420..623	CDD:279410	51/220 (23%)
pdr1	NP_593995.1	3a01205	40..1382	CDD:273362	157/616 (25%)
		ABCG_PDR_domain1	70..302	CDD:213200
		ABC2_membrane	421..620	CDD:279410
		PDR_CDR	634..>701	CDD:283960
		ABCG_PDR_domain2	755..983	CDD:213199	74/234 (32%)
		ABC2_membrane	1076..1284	CDD:279410	51/220 (23%)
		PDR_CDR	<1349..>1377	CDD:283960

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	79	1.000	Domainoid score	I2350
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9277
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
TreeFam	0	0.000	Not matched by this tool.
	3	3.000