Protein Alignment CG5853 and wht-6

DIOPT Version :9

• Sequence 1: NP_001260309.1
• Gene: CG5853 / 34322
• FlyBaseID: FBgn0032167
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_498425.2
• Gene: wht-6 / 188911
• WormBaseID: WBGene00007060
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 621
• Identity: 155/621 - (24%)
• Similarity: 275/621 - (44%)
• Gaps: 71/621 - (11%)

  Fly   102 PVDMEFKELSLTVKLGFNRGSKEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDAL--SGFKTTGV 164
            ||.:.:..:::|.    .:..:.:|.||.|.....:|:|:||.|||||:|||:.|  ...|....
 Worm    31 PVSLHWNNITVTT----IKEKRLLLKNVSGYAKSGELLALMGASGAGKTTLLNMLMCRNLKGLST 91

  Fly   165 DGSILLNGRRRDLPSFRRMSCYITQDDRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIEDILL 229
            :|:|.:||... ......:|.:..|::.....|||.|.:.|.|.|::..  |.:.:|.|:.|:|.
 Worm    92 EGTITVNGNEM-AHKISSISGFAQQEELFVGTLTVKEYLMIQAKLRING--SKKLREDRVTDVLH 153

  Fly   230 LLGLYN-HDQTLTM-----RLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKK 288
            .|.|:. .|..:.:     .:|||:.:||:.|.|:::||:::|.|||||||||.....|:::||.
 Worm   154 QLKLWKCRDSKIGVIGEKKGISGGEARRLTFACEMLSNPSLLFADEPTTGLDSFMAESVIQILKG 218

  Fly   289 LTSQGRTIICTIHQPTAKLFQIFDQVYVLSAGNCVYQGSTQKLVPFLQSVDLPCPMYHNPADYII 353
            :...|||||||||||:::|:|:|.:|..|:.|:..:||:.|:.:.|.:......|..:||:::||
 Worm   219 IAKTGRTIICTIHQPSSQLYQMFHRVIYLANGSTAFQGTPQESISFFEKCGHRVPDEYNPSEWII 283

  Fly   354 ELACGEYGY-----DKVDTLKLATENGSCLTWFHNPSAVLRAEVLMRKYPIPKKTKSRSLEDTSY 413
            .....:.|.     |::..:....|:..     |....:.:...:..|.|.|:      :...:.
 Worm   284 YKLAVQPGQEKQSNDRIQKIVEQYEDSD-----HQKRVMEQLSDVSEKIPPPE------MHRANV 337

  Fly   414 SNQCSVLLRRGFIKAKRDTTMTHLRIGVNIAVAALFGAMYDHTGREGSRVLDNYN-LLFAILMHH 477
            ..|...|..|..|...|...:|..::...|......|.:|..|..: :|.:.|.| .||.:...:
 Worm   338 FTQIFALSTRCGIDVWRAPQLTLAKVIQKILFGLFIGLLYLRTPYD-ARGIHNINGALFFLAGEY 401

  Fly   478 SMTTMMLTVLTFPMDISILIKEHFNRWYSLKAYYTAMTLVDLPISIISCFFFTVIVYLWSYQPME 542
            ..:|....:.....:..::.:|:.:..|:|..||.|..:..:|:..........|||
 Worm   402 IYSTAYAIMFFLNNEFPLVAREYHDGLYNLWTYYFARCISLIPLFSTDGLILLFIVY-------- 458

  Fly   543 WI-----RFFMFFSISLLTVFVGH---SFGLMIGAWFDVVNGTFLAPVLTIPMMMFAGFG---VT 596
            |:     ........|::||....   :||:.:...|.....|  |.:.:.|:::|..||   ..
 Worm   459 WLIGLNTSVMQVIVASIITVLASQAASAFGIAMSCIFPTAQMT--AVMASPPLVLFRLFGGLYGN 521

  Fly   597 LRDLPSYLRWGSHISYLRYGLEGFISAIYGLDRGTLACEEAPYCHYRYPKKFLEEITMRGDQFWN 661
            ....|:.:||...||..|:..||.:...:         .|....|......:....|.....::.
 Worm   522 TNTFPAAIRWLQWISMYRFAFEGLVVNQW---------SEIDDFHSNAKNNWTNSTTNDVLDYFA 577

  Fly   662 --------DVIALGVMILVFRFVSYVVLKAKIKSIR 689
                    |:|.|.::.|.|..:.::.|..::|..|
 Worm   578 FSESAIPLDIIGLILISLAFYLIGFIALVHRMKKAR 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	154/619 (25%)
		ABCG_EPDR	102..326	CDD:213180	81/231 (35%)
		ABC2_membrane	420..623	CDD:279410	46/214 (21%)
wht-6	NP_498425.2	P-loop_NTPase	<3..>81	CDD:393306	19/53 (36%)
		3a01204	50..613	CDD:273361	151/596 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R138
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.750