Protein Alignment CG5853 and wht-5

DIOPT Version :9

• Sequence 1: NP_001260309.1
• Gene: CG5853 / 34322
• FlyBaseID: FBgn0032167
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_502352.1
• Gene: wht-5 / 178182
• WormBaseID: WBGene00008950
• Length: 695
• Species: Caenorhabditis elegans
• Alignment Length: 721
• Identity: 184/721 - (25%)
• Similarity: 319/721 - (44%)
• Gaps: 144/721 - (19%)

  Fly    51 QSSVTPPPIPTPPQVNYTNGNEPSKQPPLEPVVEEEVHF--------------DTDALNNLPARE 101
            |.|.:|.|.|||..|..   |:......:|.|.:|..|.              ||::     ||.
 Worm    32 QKSRSPTPKPTPIPVLI---NDTPVASEIEQVEKELAHSSERFRKPKTLSVTNDTES-----ARI 88

  Fly   102 PVDME-------FKELSLTV--KLGFNRGSKEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALS 157
            |..::       |:.:...|  |.|..   :|||..:.|.....:|..|||.|||||:|||:.|:
 Worm    89 PSQVKTNAKKLVFQNIQAVVLKKKGVR---QEILKKIDGVARPGELTFIMGSSGAGKTTLLNILT 150

  Fly   158 G--FKTTGVDGSILLNGRRRDLPSFRRMSCYITQDDRLQPLLTVNENMHIAADLKLGQTVSYEEK 220
            |  .|....||.|::|||.......:::|.|:.|||.....|||.|.:..||.|:....:...|.
 Worm   151 GRNLKNIETDGDIMINGRNMISNEMKKLSAYVQQDDVFIGTLTVRETLRFAAKLRSPSALGATEL 215

  Fly   221 ESRIEDILLLLGLYNHDQTL--TM---RLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCT 280
            :|.::::|:::.|...:.|.  ||   .||.|::|||:.|.|::.:|.::|.||||:||||....
 Worm   216 DSIVDELLVMMSLKKCENTKVGTMTEKSLSRGERKRLAFACEILTDPPILFCDEPTSGLDSFMSH 280

  Fly   281 KVLELLKKLTSQGRTIICTIHQPTAKLFQIFDQVYVLSAGNCVYQGSTQKLVPFLQSVDLPCPMY 345
            :|::.|::||.:|:|:|||||||:..::.:.||:.:||.|:..|.|..:::..|......|.|.:
 Worm   281 QVIKALRQLTIEGKTVICTIHQPSTSVYHMADQLILLSQGHVAYAGPAKQVDAFFGRCGYPIPKF 345

  Fly   346 HNPADYIIELACGEYGYDKVDTLKLATENGSCLTWFHNPSAVLRAEVLMRKYPIPKKTKS----- 405
            .:..|:.:.:         :......||:.      :|.    |.|.::.::.|.||.:|
 Worm   346 VSSPDHFMRV---------ISHKSFETEDD------YNK----RIEKIVLEHDIMKKEQSTHSTL 391

  Fly   406 ----RSLEDT-------SYSNQCSVLLRRGFIKAKRDTTMTHLRIGVNIAVAALFGAMYDHTGRE 459
                |...:|       :::.|...:.:|..|:..|:.::..:::...:.::.:.|:.|  .|.|
 Worm   392 SSSRREHPETAPFTFPRTWTAQFFFIFQRSSIQLWRERSVLLVKLIQTLIMSIMIGSTY--YGLE 454

  Fly   460 GSRVLDNYNL-------LFAILMHHSMTTMMLTVLTFPMDISILIKEHFNRWYSLKAYYTAMTLV 517
                :|..:|       ..::.|.| |..||..:..|..|..::::|.....||..|||.|.|..
 Worm   455 ----IDKKSLPSFKGFAFVSVQMMH-MLFMMPAMTVFWKDYPVVVREFQANMYSPSAYYLAKTTA 514

  Fly   518 D--------------------LPISIISCFFFTVIVYLWSYQPMEWIRFFMFFSISLLTVFVGHS 562
            |                    ||.|::....:.:|..|                :||....||.|
 Worm   515 DSIQYLVFPVIFSGILLGMTSLPYSVVIITNYLIINIL----------------LSLNACSVGQS 563

  Fly   563 FGLMIGAWFDVVNGTFLAPVLTIPMMMFAGFGVTLRDLPSYLRWGSHISYLRYGLEGFISAIYGL 627
            |..|.|   .:..|..:.|::.:|:|:|.||.:|...:|.|....:.:|:.:||.|. |:.:|..
 Worm   564 FAAMCG---HLATGMTVLPIVCVPLMVFGGFMITYEAIPWYFLPFAWVSWYKYGFEA-ITIVYFN 624

  Fly   628 DRGTLA-CEE-----------APYCHYRYPKKFLEEITMRGDQFWNDVIALGVMILVFRFVSYVV 680
            ...|:: ||.           ...|....  :|::.........|.|...:..:||.::.:..::
 Worm   625 HNSTISGCESNSSVATLKMSIDSNCTTGI--EFIKAQAFEETHLWLDYTVILAVILFWKILGALL 687

  Fly   681 LKAKIK 686
            ...:|:
 Worm   688 FTWRIR 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	169/661 (26%)
		ABCG_EPDR	102..326	CDD:213180	86/239 (36%)
		ABC2_membrane	420..623	CDD:279410	53/229 (23%)
wht-5	NP_502352.1	3a01204	88..695	CDD:273361	167/657 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720