Protein Alignment CG5853 and wht-2

DIOPT Version :10

• Sequence 1: NP_788019.1
• Gene: CG5853 / 34322
• FlyBaseID: FBgn0032167
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_502164.1
• Gene: wht-2 / 178069
• WormBaseID: WBGene00007513
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 651
• Identity: 181/651 - (27%)
• Similarity: 301/651 - (46%)
• Gaps: 118/651 - (18%)

  Fly    94 LNNLPAREPVDMEFKELSLTVKLGFNRGSKEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSG 158
            ::.|.|.:||.:.:..:|:..:    :..|:||.||.|.....||:|:||.|||||:|||:.|..
 Worm    23 ISALEAVDPVTLTWHNISIHAE----KSGKQILENVSGIAKPGQLLALMGASGAGKTTLLNMLLS 83

  Fly   159 FKTTGVD--GSILLNGRR--RDLPSFRRMSCYITQDDRLQPLLTVNENMHIAADLKL-GQTVSYE 218
            ....|::  ||:.:||..  |.:.:   :|.|..||:.....|||.|.:.|.|.|:: |.:   |
 Worm    84 RNLRGLETSGSVKVNGHELGRGITA---ISGYAQQDELFVGTLTVKEYLDIQAKLRVNGDS---E 142

  Fly   219 EKESRIEDILLLLGLYNHDQTL------TMRLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSS 277
            ::..|:.:::..||||....|.      ...:|||:.:||:.|.||::||:::|.|||||||||.
 Worm   143 KRRRRVGNVMSQLGLYKCQNTRIGTIGGQKGISGGEMRRLTFACELLSNPSILFCDEPTTGLDSF 207

  Fly   278 SCTKVLELLKKLTSQGRTIICTIHQPTAKLFQIFDQVYVLSAGNCVYQGSTQKLVPFLQSVDLPC 342
            ....|:::|..|...|||:|||||||:::|:.:||:|..::.|...:.||.:..:.|.:.....|
 Worm   208 MAESVVQVLSNLAKSGRTVICTIHQPSSQLYLMFDRVMFMAGGKTAFLGSPRDAIQFFEDAGFAC 272

  Fly   343 PMYHNPADYIIELACGEYGYDKVDTLK-LATENGSC-------LTWFHNPSAVLRAEVLMRKYPI 399
            |...||||.||.            ||. :..|...|       .|.|.|.|   ....|  |:.:
 Worm   273 PRNFNPADLIIH------------TLAVMPNEEDKCRQRIEVIYTKFQNSS---YGRTL--KFGV 320

  Fly   400 PKKTKSRSLED---TSYSNQCSVLLRRGFIKAKRDTTMTHLRIGVNIAVAALF-GAMYDHTGREG 460
            .|..:.:...:   |....|...||.|..|...|:.::|..:: :..::..|| |.:|..:....
 Worm   321 EKSDEGQRPSERHKTGILTQIGALLERSAIDTWRNPSLTRAKV-IQKSIMGLFIGLLYLQSPLTS 384

  Fly   461 SRVLDNYNLLFAILMHHSMTTMMLTVLTFPMDISILIKEHFNRWYSLKAYYTAMTLVDLPISIIS 525
            ..:.:....||.::...:.:|:...:...|.|..::.:|:.:..||:.:||.|..|..||:
 Worm   385 IGISNLNGALFYLVCELTYSTIFGILNFLPADFPLVSREYHDGLYSVFSYYVARCLSYLPL---- 445

  Fly   526 CFFFT---VIVYLWSYQPMEWIRFFMFFSISLLTVFV-----------GHSFGLMIGAWFDVVNG 576
               ||   :|:.|.||    |:   :.||.|:..|..           ..:.|:||..
 Worm   446 ---FTADGLIMLLVSY----WM---VGFSSSITQVLYACLIAFLIEQSSSACGIMISC------- 493

  Fly   577 TFLAPVLTI------PMM--------MFAGFGVTLRDLPSYLRWGSHISYLRYGLEGFI----SA 623
              ::|.|.|      ||:        ::|..|.    ||||:.|..::|:.|||.|.|.    |:
 Worm   494 --ISPSLPIAMSTAGPMLTLLSLTGGLYANVGA----LPSYISWIQYLSWFRYGFEAFAINQWSS 552

  Fly   624 IYGLDRGTLACEEAPYCHYRYPKKFLEEITMRGDQFWNDVIALGVMILVFRFVSYVVLKAKIKSI 688
            : .....|:..:|.       ....|.:::.|.:.|:.|:..:...||:|..:.|..|..::...
 Worm   553 V-NEQNTTIWTDEK-------RDSVLSQLSFRAEMFYPDLFIMSAFILIFYTIGYAGLALRVSKA 609

  Fly   689 R 689
            |
 Worm   610 R 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_788019.1	3a01204	97..689	CDD:273361	180/646 (28%)
wht-2	NP_502164.1	3a01204	44..610	CDD:273361	175/628 (28%)