Protein Alignment CG5853 and wht-1

DIOPT Version :10

• Sequence 1: NP_788019.1
• Gene: CG5853 / 34322
• FlyBaseID: FBgn0032167
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_001348731.1
• Gene: wht-1 / 175859
• WormBaseID: WBGene00015479
• Length: 671
• Species: Caenorhabditis elegans
• Alignment Length: 649
• Identity: 183/649 - (28%)
• Similarity: 306/649 - (47%)
• Gaps: 62/649 - (9%)

  Fly    75 KQPPLEPVVEEEVHFDTDALN-NLPAREPVDMEFKELSLTVKLGFNRGSKEILHNVCGKFPGSQL 138
            :|..::|||.|..:....:|| ..|..:|.:...:..:...|    |..|||||||.|.....:|
 Worm    35 QQTGIQPVVPEGCNLYWSSLNVTGPETKPTNFVDRFRNNMPK----RRVKEILHNVSGMAESGKL 95

  Fly   139 IAIMGPSGAGKSTLLDALSGFKTTGVD--GSILLNGRRRDLPSFRRMSCYITQDDRLQPLLTVNE 201
            :||:|.|||||:||::.|:....|.:|  ||||::|||.:....|.||.::.|.|.....:|..|
 Worm    96 LAILGSSGAGKTTLMNVLTSRNLTNLDVQGSILIDGRRANKWKIREMSAFVQQHDMFVGTMTARE 160

  Fly   202 NMHIAADLKLG-QTVSYEEKESRIEDILLLLGLYNHDQTL------TMRLSGGQKKRLSIAMELI 259
            ::...|.|::| |..|..|::.|:|.:|..:||.....|:      ...||.|:|||||.|.|::
 Worm   161 HLQFMARLRMGDQYYSDHERQLRVEQVLTQMGLKKCADTVIGIPNQLKGLSCGEKKRLSFASEIL 225

  Fly   260 NNPTVMFLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQPTAKLFQIFDQVYVLSAGNCVY 324
            ..|.::|.||||:|||:.....|::.|:.|...|.|:|.|||||::.::.:|:.|.:::.|..:|
 Worm   226 TCPKILFCDEPTSGLDAFMAGHVVQALRSLADNGMTVIITIHQPSSHVYSLFNNVCLMACGRVIY 290

  Fly   325 QGSTQKLVPFLQSVDLPCPMYHNPADYIIELACGEYGYDKVDTLK---------LATENGSCLTW 380
            .|...:.||..:....|||.|:||||::|. .......|:..::|         |:|:.|..:..
 Worm   291 LGPGDQAVPLFEKCGYPCPAYYNPADHLIR-TLAVIDSDRATSMKTISKIRQGFLSTDLGQSVLA 354

  Fly   381 FHNPSAVLRAEVLMRKYPIPKKTKSRSLED--TSYSNQCSVLLRRGFIKAKRDTTMTHLRIGVNI 443
            ..|.:. |||...:......:|||:...:|  .|:..|...|..|.::...||..:..:|:...:
 Worm   355 IGNANK-LRAASFVTGSDTSEKTKTFFNQDYNASFWTQFLALFWRSWLTVIRDPNLLSVRLLQIL 418

  Fly   444 AVAALFGAMYDHTGREGSRVLDNYNLLFAILMHHSMTTMMLTVLTFPMDISILIKEHFNRWYSLK 508
            ..|.:.|.::..|....:.::....::|..:.:.:.......|.....::.|:::|:.|..|...
 Worm   419 ITAFITGIVFFQTPVTPATIISINGIMFNHIRNMNFMLQFPNVPVITAELPIVLRENANGVYRTS 483

  Fly   509 AYYTAMTLVDLPISIISCFFFTVIVYLWSYQPMEWI-----RFFMFFSISLLTVFVGH---SFGL 565
            ||:.|..:.:||..||....:..|||        |:     .|:.:...||:|:.:.:   |...
 Worm   484 AYFLAKNIAELPQYIILPILYNTIVY--------WMSGLYPNFWNYCFASLVTILITNVAISISY 540

  Fly   566 MIGAWF---DVVNGTFLAPVLTIPMMMFAGFGVTLRDLPSYLRWGSHISYLRYGLEGF------- 620
            .:...|   ||  ...:.|:..:|:|.|.||.:|...:|||.:|.|.:||.:||.|..
 Worm   541 AVATIFANTDV--AMTILPIFVVPIMAFGGFFITFDAIPSYFKWLSSLSYFKYGYEALAINEWDS 603

  Fly   621 ---ISAIYGLDRGTLACEEAPYCHYRYPKKFLEEITMRGDQFWNDVIALGVMILVFRFVSYVVL 681
               |...:.......|.:..|    :...:.||.|.........|:..|..|.:..|.::||.|
 Worm   604 IKVIPECFNSSMTAFALDSCP----KNGHQVLESIDFSASHKIFDISILFGMFIGIRIIAYVAL 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_788019.1	3a01204	97..689	CDD:273361	176/626 (28%)
wht-1	NP_001348731.1	3a01204	76..667	CDD:273361	174/608 (29%)