DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5853 and abt-2

DIOPT Version :9

Sequence 1:	NP_001260309.1	Gene:	CG5853 / 34322	FlyBaseID:	FBgn0032167	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_490949.3	Gene:	abt-2 / 171782	WormBaseID:	WBGene00000020	Length:	2146	Species:	Caenorhabditis elegans

Alignment Length:	407	Identity:	97/407 - (23%)
Similarity:	162/407 - (39%)	Gaps:	89/407 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 VEEEVHFDTDALNNLPAREPVDMEFKELSLTVKLG-----FNRGSKEI------LHNVCGKFPGS 136
            |::| ||||     :|..:..|.|...|:|.|.:.     :..|:|.:      |:.       .
Worm   904 VDDE-HFDT-----IPNSDSFDSEPTNLTLAVHINSMSKVYENGTKALDCLNLRLYE-------G 955

  Fly   137 QLIAIMGPSGAGKSTLLDALSG-FKTTGVDGSILLNGRRRDLPSFRRMSCYITQDDRLQPLLTVN 200
            |:..::|.:||||:|.:..|.| :..:.....|.....|.||...|.:.....|.:.|...|||:
Worm   956 QITGLLGHNGAGKTTTMSILCGLYAPSSGTAKIYQRDIRTDLRRVRDVLGICPQHNVLFSHLTVS 1020

  Fly   201 ENMHIAADLKLGQTVSYEEKESRIEDILLLLGLYNHDQTLTMRLSGGQKKRLSIAMELINNPTVM 265
            |.:.:.|.||   .|...|..|::::||..:.|......|...||||.|:||.|.:..|.....:
Worm  1021 EQLRLFAALK---GVPDSELTSQVDEILASVSLTEKANKLASTLSGGMKRRLCIGIAFIGGSRFV 1082

  Fly   266 FLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIH---------QPTAKLFQIFDQVYVLSAGN 321
            .|||||.|:|.::...:.:||:: ..:||||:.:.|         ...|.|.|.|::..:|....
Worm  1083 ILDEPTAGVDVTARKDIWKLLQR-NKEGRTILLSTHHMDEADVLSDRIAILSQDFEKPDLLDGKR 1146

  Fly   322 CVYQG-------------------STQKLVP-FLQSV--------------DLPCPMYHNPADYI 352
            .::|.                   ..|.::| ||.::              ||...|...|.:..
Worm  1147 LIFQHFYALLVCRINYTLKSKRTFLFQVIIPLFLLALAELFVLLQVSTARPDLMVSMPPLPLETS 1211

  Fly   353 IELACGEYGYDKVDTLKLATENGSCLTWFHNPSA--------------VLRAEVLMR-KYPIPKK 402
            |.....::..:..||.:.:|.|......|.:|..              .:|.|::.| :|...:.
Worm  1212 IMGNHSDFYVNSWDTAENSTANDILHAMFSSPGTGPRCAKDVPNDLLDTMRRELMFRNRYGFGRN 1276

  Fly   403 TKSRSLEDTSYSN--QC 417
            ..:..::..|..|  ||
Worm  1277 KPAPGVDKDSVDNEYQC 1293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	91/393 (23%)
		ABCG_EPDR	102..326	CDD:213180	66/244 (27%)
		ABC2_membrane	420..623	CDD:279410
abt-2	NP_490949.3	rim_protein	39..2117	CDD:130324	97/407 (24%)
		ABC_subfamily_A	929..1134	CDD:213230	59/215 (27%)
		ABC_subfamily_A	1802..2024	CDD:213230
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000