Protein Alignment CG5853 and w

DIOPT Version :10

• Sequence 1: NP_788019.1
• Gene: CG5853 / 34322
• FlyBaseID: FBgn0032167
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: XP_061509581.1
• Gene: w / 1271671
• VectorBaseID: AGAMI1_013186
• Length: 722
• Species: Anopheles gambiae
• Alignment Length: 753
• Identity: 191/753 - (25%)
• Similarity: 321/753 - (42%)
• Gaps: 143/753 - (18%)

  Fly    28 VTSSRVYNS---------------------TTVPVGNSGGWRNAQSSVTPPPIPTPPQVNYT--- 68
            ::|||.|:|                     |.:.|     |:..........||...::.||
Mosquito    18 ISSSRRYSSSSYQDQSMDDALNTTLTNDKATLIQV-----WKPKSYGSVKGQIPQCERLTYTWKE 77

  Fly    69 ---NGNEPSKQPPLEPVVEEEVHFDTDALNNLPAREPVDMEFKELSLTVKLGFNRGSKEILHNVC 130
               .|..|:...|.||:...        |.|...|:..|             || ..|.:|.||.
Mosquito    78 IDVFGEAPTDGKPREPLCTR--------LRNCCTRQRKD-------------FN-PRKHLLKNVT 120

  Fly   131 GKFPGSQLIAIMGPSGAGKSTLLDALSGFKTTGV----DGSILLNGRRRDLPSFRRMSCYITQDD 191
            |.....:|:|:||.|||||:|||:||:.....||    :....|||...:....|....|:.|||
Mosquito   121 GVAKSGELLAVMGSSGAGKTTLLNALAFRSPPGVKISPNAVRALNGVPVNAEQLRARCAYVQQDD 185

  Fly   192 RLQPLLTVNENMHIAADLKLGQTVSYEEKESRIEDILLLLGLYNHDQTL------TMRLSGGQKK 250
            ...|.||..|::...|.|::|:.|....|:.|::::|..|.|.....|:      ...||||::|
Mosquito   186 LFIPSLTTREHLLFQAMLRMGRDVPASVKQHRVQEVLQELSLVKCADTIIGAPGRIKGLSGGERK 250

  Fly   251 RLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQPTAKLFQIFDQVY 315
            ||:.|.|.:.:|.::..||||:||||.....||::||.:..:|:|||.|||||:::|:.:||::.
Mosquito   251 RLAFASETLTDPHLLLCDEPTSGLDSFMAHSVLQVLKGMAMKGKTIILTIHQPSSELYCLFDKIL 315

  Fly   316 VLSAGNCVYQGSTQKLVPFLQSVDLPCPMYHNPADYIIEL-----------------ACGEYGYD 363
            :::.|...:.||..:...|...:.:|||..:||||:.:::                 .|..:...
Mosquito   316 LVAEGRVAFLGSPYQSAEFFSQLGIPCPPNYNPADFYVQMLAIAPAKEAECRDMIKKICDSFAVS 380

  Fly   364 KV--DTLKLATENGSCLTWFHNPSAVLRAEVLMRKYPIPKKTKSRSLEDTSYSNQCSVLLRRGFI 426
            .:  :.|:.|:..|..:   ..|..:.:.|.:       ..|..||    |:..|...:|.|.::
Mosquito   381 PIAREVLETASVAGKGM---DEPYMLQQVEGV-------GSTGYRS----SWWTQFYCILWRSWL 431

  Fly   427 KAKRDTTMTHLRIGVNIA---------------------------VAALFGAMYDHTGREGSRVL 464
            ...:|..:..:|: :..|                           ||.|.|::|.....:...|:
Mosquito   432 SVLKDPMLVKVRL-LQTAVGSRGPSSDLPELTTCFPCFFSPRPQMVATLIGSIYFGQVLDQDGVM 495

  Fly   465 DNYNLLFAILMHHSMTTMMLTVLTFPMDISILIKEHFNRWYSLKAYYTAMTLVDLPISIISCFFF 529
            :....||..|.:.:...:...:..|..::.:.::|..:|.|.:..|:...|:.:||:.|...|.|
Mosquito   496 NINGSLFLFLTNMTFQNVFAVINVFSAELPVFLREKRSRLYRVDTYFLGKTIAELPLFIAVPFVF 560

  Fly   530 TVIVYLWSYQPMEWIR-----FFMFFSISLLTVFVGHSFGLMIG-AWFDVVNGTFLAPVLTIPMM 588
            |.|.|     ||..:|     :.....|..|...|..|||.:|. |...:.....:.|.:.||.:
Mosquito   561 TSITY-----PMIGLRTGATHYLTTLFIVTLVANVSTSFGYLISCASSSISMALSVGPPVVIPFL 620

  Fly   589 MFAGFGVTLRDLPSYLRWGSHISYLRYGLEGFI----SAIYGLDRGTLACEEAPYCHYRYPKKFL 649
            :|.||.:....:|:|.::.|::|:.||..|..:    |.:..   |.:||..|.....|..:..|
Mosquito   621 IFGGFFLNSASVPAYFKYLSYLSWFRYANEALLINQWSTVVD---GEIACTRANVTCPRSGEIIL 682

  Fly   650 EEITMRGDQFWNDVIALGVMILVFRFVSYVVLKAKIKS 687
            |....|.:.|..|:..|..:|::||..:.:.|..:.:|
Mosquito   683 ETFNFRVEDFALDIACLFALIVLFRLGALLCLWLRSRS 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_788019.1	3a01204	97..689	CDD:273361	172/657 (26%)
w	XP_061509581.1	None