Protein Alignment CG5853 and Abcg5

DIOPT Version :9

• Sequence 1: NP_001260309.1
• Gene: CG5853 / 34322
• FlyBaseID: FBgn0032167
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_446206.2
• Gene: Abcg5 / 114628
• RGDID: 620298
• Length: 652
• Species: Rattus norvegicus
• Alignment Length: 605
• Identity: 166/605 - (27%)
• Similarity: 289/605 - (47%)
• Gaps: 68/605 - (11%)

  Fly   123 KEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSG-FKTTG-VDGSILLNG--RRRDLPSFRRM 183
            ::||.:|.......|.:.|:|.||:||:|||||:|| .:.|| ::|.:.:||  .|||  .|:..
  Rat    67 RKILKDVSLYIESGQTMCILGSSGSGKTTLLDAISGRLRRTGTLEGEVFVNGCELRRD--QFQDC 129

  Fly   184 SCYITQDDRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIEDILL----------LLGLYNHDQ 238
            ..|:.|.|.....|||.|.:...|.|.| ::.|.:..:.::|.:|.          ::|.||..
  Rat   130 VSYLLQSDVFLSSLTVRETLRYTAMLAL-RSSSADFYDKKVEAVLTELSLSHVADQMIGNYNFG- 192

  Fly   239 TLTMRLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQP 303
                .:|.|:::|:|||.:|:.:|.||.|||||||||..:...::.||.:|..:.|.:|.|||||
  Rat   193 ----GISSGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMTANHIVLLLVELARRNRIVIVTIHQP 253

  Fly   304 TAKLFQIFDQVYVLSAGNCVYQGSTQKLVPFLQSVDLPCPMYHNPADYIIELACGE--------Y 360
            .::||..||::.:|:.|..|:.|:.::::.|..:...|||.:.||.|:.::|...:        .
  Rat   254 RSELFHHFDKIAILTYGELVFCGTPEEMLGFFNNCGYPCPEHSNPFDFYMDLTSVDTQSREREIE 318

  Fly   361 GYDKVDTLKLA-TENGSCLTWFHNPSAVLRAEVLMRKYPIPKKTKSRSLEDTSYSNQCSVLLRRG 424
            .|.:|..|:.| .::..|.....|   :.|...|.....:|.|||:    ......:..|||||.
  Rat   319 TYKRVQMLESAFRQSDICHKILEN---IERTRHLKTLPMVPFKTKN----PPGMFCKLGVLLRRV 376

  Fly   425 FIKAKRDTTMTHLRIGVNIAVAALFGAMY----DHTGREGSRVLDNYNLLFAILMHHSMTTMMLT 485
            .....|:..:..:|:..|: :..||...|    .:...:|: |.|...||:.::.....|.|:..
  Rat   377 TRNLMRNKQVVIMRLVQNL-IMGLFLIFYLLRVQNNMLKGA-VQDRVGLLYQLVGATPYTGMLNA 439

  Fly   486 VLTFPMDISILIKEH----FNRWYSLKAYYTAMTLVDLPISIISCFFFTVIVYLWSYQPMEWIRF 546
            |..|||..::..:|.    :.:|..|.||    .|..||.||::...|:.:.| |:......:..
  Rat   440 VNLFPMLRAVSDQESQDGLYQKWQMLLAY----VLHALPFSIVATVIFSSVCY-WTLGLYPEVAR 499

  Fly   547 FMFFSISLLTV-FVGHSFGLMIGAWF---DVVNGTFLAPVLTIP-MMMFAGFGVTLRDLPSYLRW 606
            |.:||.:||.. .:|....|::....   ::||.  :..:|:|. :::.:||...:.::|..|:.
  Rat   500 FGYFSAALLAPHLIGEFLTLVLLGMVQNPNIVNS--IVALLSISGLLIGSGFIRNIEEMPIPLKI 562

  Fly   607 GSHISYLRYGLEGF-ISAIYGLD----RGTLACEEAPYCHYRYPKKFLEEITMRG--DQFWNDVI 664
            ..:.::.:|..|.. ::..|||:    ....:....|.|......:|:|: |..|  .:|..:.:
  Rat   563 LGYFTFQKYCCEILVVNEFYGLNFTCGGSNTSVPNNPMCSMTQGIQFIEK-TCPGATSRFTTNFL 626

  Fly   665 ALGVMILVFRFVSYVVLKAK 684
            .|...|.....:..||.|.:
  Rat   627 ILYSFIPTLVILGMVVFKVR 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	166/605 (27%)
		ABCG_EPDR	102..326	CDD:213180	78/216 (36%)
		ABC2_membrane	420..623	CDD:279410	51/216 (24%)
Abcg5	NP_446206.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		ABCG_White	50..276	CDD:213201	78/216 (36%)
		3a01204	61..646	CDD:273361	166/603 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820