DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5853 and abca1

DIOPT Version :9

Sequence 1:	NP_001260309.1	Gene:	CG5853 / 34322	FlyBaseID:	FBgn0032167	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	XP_004910916.1	Gene:	abca1 / 100491942	XenbaseID:	XB-GENE-1001143	Length:	2311	Species:	Xenopus tropicalis

Alignment Length:	365	Identity:	98/365 - (26%)
Similarity:	162/365 - (44%)	Gaps:	72/365 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 IPTPPQVNYTNG----------NEPS--KQPPLEPVVEEEVHFDTDALNNLPAREPVDMEFKELS 111
            ||.|....:|..          |:|.  ::...|..:|||           |:..|:.:..:.|
Frog   856 IPRPWYFPFTKSYWCGEECKEYNQPHTVQKGSSEVCMEEE-----------PSHLPLGVSIQNL- 908

  Fly   112 LTVKLGFNRGSKEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSGF--KTTGVDGSILLNGRR 174
              ||: :..|.|..:..:...|...|:.:.:|.:||||:|.:..|:|.  .|||. ..|:....|
Frog   909 --VKI-YRNGKKVAVDGLTLNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTTGT-AYIMKKDIR 969

  Fly   175 RDLPSFRRMSCYITQDDRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIEDILLLLGLYNHDQT 239
            .:|.|.|:......|.:.|...|||.|::...|.||   .:|.|:.::.:|.::..:||.:..:.
Frog   970 TELNSIRQNLGVCPQHNVLFDALTVEEHIWFYARLK---GLSEEKVKAEMEQMVNDVGLPHKKKY 1031

  Fly   240 LTMRLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKKLTSQGRTII-CTIHQP 303
            .|.:||||.:::||:|:..:....|:.|||||.|:|..|...:.|||.|. .|||||| .|.|..
Frog  1032 KTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLIKY-RQGRTIILSTHHMD 1095

  Fly   304 TAKLFQIFDQVYVLSAGNCVYQGSTQKLVPFLQSVDLPCPMYHNPADYIIELACGEYGYDKVDTL 368
            .|.:  :.|::.::|.|.....||:.    ||::                :|..|.|       |
Frog  1096 EADI--LGDRIAIISHGKLCCVGSSL----FLKN----------------QLGTGYY-------L 1131

  Fly   369 KLA-TENGSCLTWFHNPSAVL-------RAEVLMRKYPIP 400
            .|. .:|.|.|:...|.|:.:       ..:...:::|.|
Frog  1132 TLVKRDNDSSLSSCRNSSSTMSYLKKESSKQTACKQHPSP 1171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	88/315 (28%)
		ABCG_EPDR	102..326	CDD:213180	71/226 (31%)
		ABC2_membrane	420..623	CDD:279410
abca1	XP_004910916.1	rim_protein	1..2272	CDD:130324	98/365 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000