Protein Alignment CG4619 and FASTKD5

DIOPT Version :10

• Sequence 1: NP_609329.3
• Gene: CG4619 / 34321
• FlyBaseID: FBgn0032166
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_068598.1
• Gene: FASTKD5 / 60493
• HGNCID: 25790
• Length: 764
• Species: Homo sapiens
• Alignment Length: 598
• Identity: 124/598 - (20%)
• Similarity: 216/598 - (36%)
• Gaps: 139/598 - (23%)

  Fly     9 AGVTNLGCP------------------IRTYASLTPRDVLRS--SDETGTLLTRFAKHIALERYR 53
            |....||.|                  :|.:..|.|...:.|  :.||..||:.....:.|.:.|
Human    88 ASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQLRPEYRVHSYNASETSQLLSVSEGELILHKVR 152

  Fly    54 DSDHVLPKTTVRYSDFFPITDDRYFQRTVEKTDAAQLPALIIQASSYRSNAAVPMYVTALNTLDN 118
            .:.:.|....        |.|   :...:....|.|.|.|:..              |:...|..
Human   153 VNQNNLQAQV--------IVD---YLCKLSSLPAEQHPVLLGS--------------TSFALLCQ 192

  Fly   119 HAAKQLDKMDTATVLETLYSFLFL-IPSWIKRLDFYQAAM----------QRLVRED---FRGNK 169
            .:.|::...||..::..|.:|:.| ||.....||.|:...          |.|:..|   :.|.|
Human   193 LSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLGRK 257

  Fly   170 -ERFVQV-CFYMGLQKK----------------QAKSSEEFQQLLEEHLQTHLPELNEMDLAVVS 216
             .||:.: ..|:.|..|                ..:.|::..|.||..:..::..:|..::..:.
Human   258 VPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQKLESLILKYIDLINLEEVGTIC 322

  Fly   217 NAAYKTSTLVTGEAKTAYEARLVNAILNLEINTGSDALLVSFVKALRLQQVKDERVCQHLQDICL 281
            ...:|:||.:     :.:..|.:..:....|...|...||:.||..|...|......:.:.:|.
Human   323 LGFFKSSTNL-----SEFVMRKIGDLACANIQHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIA- 381

  Fly   282 DPVKITHIEPRGLAHIFAFFAEQLWDQNECLTVVVKRLMTLLKP--GDLRSKDLATFLWASAQLN 344
             |.:|..:..:|:.|: ..:...|...||   .|:..:...|.|  ...||||:|..||:...||
Human   382 -PQRIPSLGVQGVMHL-TLYCSALRFLNE---GVMNAVAASLPPRVAHCRSKDVAKILWSFGTLN 441

  Fly   345 CALTPEEIRQLELTAL----RKLDHGEYEYFPDNLVDTCLSLCTLGHYSKDLINAAEE---LKAA 402
              ..|....:...:.:    ||:.  |:..:|::|....|.|..|.::..:||:.|..   ::.|
Human   442 --YKPPNAEEFYSSLISEIHRKMP--EFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLA 502

  Fly   403 QKRQRAQPKVD--SRLIVLRSAVAIEQPSIAKVKTERAFKEFDG--APAYLLKDRPDLTKYAQEL 463
            |:|    .|.|  ..|..|...|.||.|            ::.|  ...:|.::..:|..|..|.
Human   503 QER----TKFDLLKELYTLDGTVGIECP------------DYRGNRLSTHLQQEGSELLWYLAEK 551

  Fly   464 SGDADVEGVDVVC---PIVG--------INLPSLRVQTMGAQESVYFVELLTAEQTLKFSKKPTS 517
            ..::..|.::.|.   .::|        :.||..|...:..|..|..       :.|.|:::.|.
Human   552 DMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNL-------KPLPFNREATP 609

  Fly   518 LIRLKKRLLESLG 530
            ...:.|..||.:|
Human   610 AENVAKLRLEHVG 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4619	NP_609329.3	None
FASTKD5	NP_068598.1	RESC6-like	166..442	CDD:480594	64/302 (21%)
		FAST_1	430..503	CDD:461999	17/76 (22%)
		FAST_2	511..602	CDD:462448	19/109 (17%)
		RAP	699..758	CDD:214932