Protein Alignment CG4619 and Fastkd5

DIOPT Version :10

• Sequence 1: NP_609329.3
• Gene: CG4619 / 34321
• FlyBaseID: FBgn0032166
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_937819.3
• Gene: Fastkd5 / 380601
• MGIID: 2139469
• Length: 762
• Species: Mus musculus
• Alignment Length: 687
• Identity: 136/687 - (19%)
• Similarity: 239/687 - (34%)
• Gaps: 189/687 - (27%)

  Fly    19 RTYASLTPRDVLRSSDETGTLLTRFAKHIALERYRDSDHVLPKTTVRYSDFFPITDDRYFQRTVE 83
            |.:..|.|...|.|.:.:.|.....|..:.|        :|.|.|...:...|.....||.:
Mouse   115 RVFLKLRPEYQLHSYNRSDTHQPIAASEVEL--------ILHKVTFYQNKLQPEVITNYFYK--- 168

  Fly    84 KTDAAQLPA----LIIQASSYRSNAAVPMYVTALNTLDNHAAKQLDKMDTATVLETLYSFLFL-I 143
               .:.|||    :::.::|:           ||  |...:.|.:...:|:.::..|.:|:.| |
Mouse   169 ---LSSLPAEQNSVLLSSNSF-----------AL--LCQLSVKNIQLFNTSDLISILKAFVDLRI 217

  Fly   144 PSWIKRLDFYQAAM----------QRLVREDFRGN----KERFVQVCF-YMGLQKKQAKSS---- 189
            |..:..||.|:...          |.|:..|...|    ..||.::.| |:.|..::...|
Mouse   218 PPSLSMLDVYETRFCHQVWEMTLDQLLLVADLWRNLGRRVPRFFKIFFSYLNLHWRELSLSQLIH 282

  Fly   190 ------------EEFQQLLEEHLQTHLPELNEMDLAVVSNAAYKTSTLVTGEAKTAYEARLVNAI 242
                        ::..|.||..:..::..:|..::..:....:|:|:     :.:.:..|.:..:
Mouse   283 LIYIIGENRQVPQDLMQRLESLILKYVDSVNLEEVGTICLGFFKSSS-----SLSEFVMRKIGDL 342

  Fly   243 LNLEINTGSDALLVSFVKALRLQQVKDERVCQHLQDICLDPVKITHIEPRGLAHI-FAFFAEQLW 306
            ....:...|...||..:|..|...|......:...:|.  |.:|..:..:|:.|: .|..|.::.
Mouse   343 ACANMQHLSSHTLVHILKMFRFTHVDHIHFMKQFGEIA--PQRIPSLGVQGVMHLTLACSALRIL 405

  Fly   307 DQNECLTVVVKRLMTLLKP--GDLRSKDLATFLWASAQLNCALTPEEIRQLELTALRKLDH--GE 367
            |:.     |:..:...|.|  ...||||:|..||:...||  ..|....:...:.:.::..  .|
Mouse   406 DER-----VMNAVAASLPPRVAHCRSKDVAKILWSFGTLN--YKPPNTEEFYSSLINEIHRKMPE 463

  Fly   368 YEYFPDNLVDTCLSLCTLGHYSKDLINAAEE---LKAAQKRQRAQPKVDSRLIVLRSAVAIEQP- 428
            :..:|::|:...:.|....::..:.||.|..   :|.||:|.:.:  :...|..|...||||.|
Mouse   464 FNQYPEHLLTCLIGLAFSEYFPVEFINVALSPGFVKLAQERSKFE--LTKELFTLDGTVAIECPD 526

  Fly   429 -------SIAKVKTER-----AFKEFDGAP-----AYLLKDR---PDLTKYAQEL----SGDADV 469
                   |..:.:|..     |.|:....|     .|||:..   |...|:...|    |.|.:|
Mouse   527 YKGNRLNSHLQQETSANLWNLASKDMRSKPEFLETLYLLETMLGGPQYIKHHMILPHTRSSDLEV 591

  Fly   470 -------------------EGVDVVCPIVGINL-PSLRVQTMGAQESVYF---VELLTAEQTLKF 511
                               :|..:....||::| ..|..|.:..:...||   :||.|.:..::.
Mouse   592 QLDANMKPMPFNSEATPTEDGAQLRFKQVGVSLTDDLMNQLLKGKAKRYFQGQIELETGQPPMEL 656

  Fly   512 SKKPT----------------------------------------------------SLIRLKKR 524
            .||.|                                                    .|..:|:|
Mouse   657 RKKTTVPLVNSGCNGTDRLGDGMVGLCPLAHMQPPLVKLAIQFTNKNQYCYGSRALLGLHNMKRR 721

  Fly   525 LLESLGRKVVVLNSTEMATNAKELRQLLEPAANAGEE 561
            .|..:|.:||.|...|.....|..|  ||..|...|:
Mouse   722 QLVQIGYRVVELPHWEWLPLLKRTR--LEKLAYLHEK 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4619	NP_609329.3	None
Fastkd5	NP_937819.3	RESC6-like	163..441	CDD:480594	62/310 (20%)
		FAST_1	429..498	CDD:461999	13/70 (19%)
		FAST_2	511..601	CDD:462448	21/89 (24%)
		RAP	697..756	CDD:214932	14/60 (23%)