DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42366 and AT5G45430

DIOPT Version :9

Sequence 1:	NP_723501.2	Gene:	CG42366 / 34319	FlyBaseID:	FBgn0259712	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	NP_568646.1	Gene:	AT5G45430 / 834579	AraportID:	AT5G45430	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	552	Identity:	221/552 - (40%)
Similarity:	300/552 - (54%)	Gaps:	79/552 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLSHPNIVKL 65
            |.||..|.::||||:|.|.....|.|.|.|||||||:||:||||.:||||||||.:::|||||||
plant     1 MERYTLLKEVGDGTFGNVWRAVNKQTNEVVAIKRMKKKYFSWEECVNLREVKSLSRMNHPNIVKL 65

  Fly    66 KEVIRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRDLKPEN 130
            ||||||||.||||||||:.||||::|||..|..|.::::..|||..||::||:.|:|||||||||
plant    66 KEVIRENDILYFVFEYMECNLYQLMKDRPKHFAESDIRNWCFQVFQGLSYMHQRGYFHRDLKPEN 130

  Fly   131 LLCSGPDLIKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYT 195
            ||.| .|:|||||.||||||.|.||:|:||||||||||||||.|..|.|.:|:||||.|||||.:
plant   131 LLVS-KDVIKIADLGLAREIDSSPPYTEYVSTRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLS 194

  Fly   196 FRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFRYPDCIKVPLSSVVSRCSQNGLDL 260
            .||||||:||.|:::|||||:|:|.::.|.:|..|||:|::::|....|.||||:...|.:.::|
plant   195 LRPLFPGASEADEIYKICSVIGSPTEETWLEGLNLASVINYQFPQFPGVHLSSVMPYASADAVNL 259

  Fly   261 LEDMLAYDPDKRPTAQQSLKYPYFHALKRISPTAATKANVRLNSKYAASNGHPVQSVSNNVLPVQ 325
            :|.:.::||..|||..::|::|:|.:...|.|:        |..|.:...|...|..|...||..
plant   260 IERLCSWDPCNRPTTAEALQHPFFQSCYYIPPS--------LRPKLSEPRGSLEQQQSVKRLPAA 316

  Fly   326 EKLQAVTELLHQTNNNMNSHSNLGKNNNLAPKNGGVPRKYQPKLSFLTTSEMGAGSHADSSSLVG 390
            ....|        |..:|::.....|   ||.:.||.....||    |.:....|.::..::...
plant   317 PTYNA--------NKPLNTYVTPKTN---APFSNGVNSYVTPK----TNAPFSNGVNSYVTAKTN 366

  Fly   391 GATVDGVPVPQHQNGGESINDIYLNRNISQLFGLPAGPQHQQQQQVHHPNVSFSTTSSRNAGAIY 455
            ....:||                 |..::.....|......||:        ..||::.|....:
plant   367 APFSNGV-----------------NNYVAPKMNAPFDNGATQQK--------VDTTNNNNQNTAW 406

  Fly   456 VNGSHLSYDTANMNAKNNAKFVVGASNGGYYVPVARPSLLGPDAKVYNVFSKVSASQAPPSLIVR 520
            .|....||     |.|::.           |.|..|.|.|....:...|||: .||:....|
plant   407 NNKPVRSY-----NVKDSK-----------YRPPGRKSPLAASMEKNWVFSR-GASETANKL--- 451

  Fly   521 QPQLQPEVAPAPMRLSGRSRAAAAVQDPKMGA 552
                      |...:.||...:...|.|.|.|
plant   452 ----------ANATIGGRWTQSQRQQQPAMKA 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	165/279 (59%)
CG42366	NP_723501.2	S_TKc	4..284	CDD:214567	165/279 (59%)
AT5G45430	NP_568646.1	STKc_MAK_like	4..283	CDD:270824	165/279 (59%)
AT5G45430	NP_568646.1	S_TKc	4..283	CDD:214567	165/279 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	356	1.000	Domainoid score	I203
eggNOG	1	0.900	-	-		E1_KOG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	361	1.000	Inparanoid score	I585
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001823
OrthoInspector	1	1.000	-	-		otm3478
orthoMCL	1	0.900	-	-		OOG6_101384
Panther	1	1.100	-	-	O	PTHR24055
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1184
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.820