DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42366 and AT4G19110

DIOPT Version :9

Sequence 1:	NP_723501.2	Gene:	CG42366 / 34319	FlyBaseID:	FBgn0259712	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	NP_849407.1	Gene:	AT4G19110 / 827649	AraportID:	AT4G19110	Length:	464	Species:	Arabidopsis thaliana

Alignment Length:	445	Identity:	203/445 - (45%)
Similarity:	283/445 - (63%)	Gaps:	59/445 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLSHPNIVKL 65
            |:||..:.::||||:|:|.....|.|||.||||:||:|||||:|.:||||||||::::|||||||
plant     1 MDRYKLIKEVGDGTFGSVWRAINKQTGEVVAIKKMKKKYYSWDECINLREVKSLRRMNHPNIVKL 65

  Fly    66 KEVIRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRDLKPEN 130
            ||||||||.||||||||:.||||::|||.....|.::|:..|||..||::||:.|:|||||||||
plant    66 KEVIRENDILYFVFEYMECNLYQLMKDRQKLFAEADIKNWCFQVFQGLSYMHQRGYFHRDLKPEN 130

  Fly   131 LLCSGPDLIKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYT 195
            ||.| .|:|||||||||||:.|.||||:||||||||||||||.|..|.|.:|:||||.|||||.:
plant   131 LLVS-KDIIKIADFGLAREVNSSPPFTEYVSTRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLS 194

  Fly   196 FRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFRYPDCIKVPLSSVVSRCSQNGLDL 260
            .||:|||:||.|:::|||||:|||.::.|.:|..||:.|::::|....|||||::...|::.::|
plant   195 LRPIFPGASEADEIYKICSVIGTPTEETWLEGLNLANTINYQFPQLPGVPLSSLMPSASEDAINL 259

  Fly   261 LEDMLAYDPDKRPTAQQSLKYPYFHALKRISPTAATKANV---------RLNSKYAASNGHPVQS 316
            :|.:.::||..||||.:.|::|:|.:...:.|:...|.:|         |.:.::.:...:|| |
plant   260 IERLCSWDPSSRPTAAEVLQHPFFQSCFYVPPSLRPKPSVARTPPPVGPRGSFEHQSVKRYPV-S 323

  Fly   317 VSN------NVLP---------VQEKLQAVTELLHQTNNNMNSHSNL--------GKNNNLAPKN 358
            ::|      .|.|         ||.||..|.:  ..|.|.....|::        ||.   :|.|
plant   324 LANAKPFNSYVSPKSNAAFGSGVQRKLDMVNQ--DGTRNTKPVRSSVRDSKYRPPGKK---SPHN 383

  Fly   359 GGVPRKYQPKLSFLTTSE---------MGA-GSHADSSSLVGGATVDGVPVPQHQ 403
            .......:.:::..:.||         :|| ||...|.|:||          |||
plant   384 AAAASLNKNRVTRSSVSETADKLANMTIGATGSRRHSVSVVG----------QHQ 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	165/279 (59%)
CG42366	NP_723501.2	S_TKc	4..284	CDD:214567	165/279 (59%)
AT4G19110	NP_849407.1	STKc_MAK_like	4..283	CDD:270824	165/279 (59%)
AT4G19110	NP_849407.1	S_TKc	4..283	CDD:214567	165/279 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	356	1.000	Domainoid score	I203
eggNOG	1	0.900	-	-		E1_KOG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	361	1.000	Inparanoid score	I585
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001823
OrthoInspector	1	1.000	-	-		otm3478
orthoMCL	1	0.900	-	-		OOG6_101384
Panther	1	1.100	-	-	O	PTHR24055
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1184
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.820