DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42366 and MHK

DIOPT Version :9

Sequence 1:	NP_723501.2	Gene:	CG42366 / 34319	FlyBaseID:	FBgn0259712	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	NP_001031622.1	Gene:	MHK / 826915	AraportID:	AT4G13020	Length:	444	Species:	Arabidopsis thaliana

Alignment Length:	423	Identity:	179/423 - (42%)
Similarity:	259/423 - (61%)	Gaps:	40/423 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLSHPNIVKL 65
            |.||..|.:|||||.|:|......:|.|.||:|:||||:|.|||.:||||||:|:||:||:|:||
plant     9 MCRYKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECVNLREVKALRKLNHPHIIKL 73

  Fly    66 KEVIRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRDLKPEN 130
            ||::||::.|:|:||.|..|||.::|:|:....|.|::|.:.|:|.|||.||::|:|||||||||
plant    74 KEIVREHNELFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQMLQGLAHMHKNGYFHRDLKPEN 138

  Fly   131 LLCSGPDLIKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYT 195
            ||.:. :::||||||||||:.|.||:|:||||||||||||||.|:.|...:|:||:|.|:||||.
plant   139 LLVTN-NILKIADFGLAREVASMPPYTEYVSTRWYRAPEVLLQSSLYTPAVDMWAVGAILAELYA 202

  Fly   196 FRPLFPGSSEVDQLFKICSVLGTPDKDDWPDG---YRLASMIHFRYPDCIKVPLSSVVSRCSQNG 257
            ..|||||.||:|||:|||.|||.||...:|:.   .|:.|:.|..:|   :..::.::...:...
plant   203 LTPLFPGESEIDQLYKICCVLGKPDWTTFPEAKSISRIMSISHTEFP---QTRIADLLPNAAPEA 264

  Fly   258 LDLLEDMLAYDPDKRPTAQQSLKYPYF----------HALKRISPTAATKANVRLNSKYAASNGH 312
            :||:..:.::||.|||||.::|.:|:|          |.|:......|...|:.||  ....|..
plant   265 IDLINRLCSWDPLKRPTADEALNHPFFSMATQASYPIHDLELRLDNMAALPNLELN--LWDFNRE 327

  Fly   313 PVQ---SVSNNVLPVQEKLQAVTELLHQTNNNMNSHSNLGKNNNLAPKNGGVPRKYQPKL--SFL 372
            |.:   .::..|.|...||    |:|...:.:|:      :|....|   ||....:|.:  |.|
plant   328 PEECFLGLTLAVKPSAPKL----EMLRNVSQDMS------ENFLFCP---GVNNDREPSVFWSLL 379

  Fly   373 TTSEMGAGSHADSSSLVGGATVDGVPVPQHQNG 405
            :..|.|..:..:||.|   :.....|:.||..|
plant   380 SPDENGLHAPVESSPL---SLSFSSPMQQHTVG 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	145/282 (51%)
CG42366	NP_723501.2	S_TKc	4..284	CDD:214567	145/282 (51%)
MHK	NP_001031622.1	STKc_MAK_like	12..291	CDD:270824	145/282 (51%)
MHK	NP_001031622.1	S_TKc	12..291	CDD:214567	145/282 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	356	1.000	Domainoid score	I203
eggNOG	1	0.900	-	-		E1_KOG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001823
OrthoInspector	1	1.000	-	-		otm3478
orthoMCL	1	0.900	-	-		OOG6_101384
Panther	1	1.100	-	-	LDO	PTHR24055
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1184
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.770