Protein Alignment CG42366 and mak

DIOPT Version :10

• Sequence 1: NP_723501.2
• Gene: CG42366 / 34319
• FlyBaseID: FBgn0259712
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_012820404.1
• Gene: mak / 780268
• XenbaseID: XB-GENE-490935
• Length: 650
• Species: Xenopus tropicalis
• Alignment Length: 697
• Identity: 274/697 - (39%)
• Similarity: 379/697 - (54%)
• Gaps: 146/697 - (20%)

  Fly     1 MNRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLSHPNIVKL 65
            ||||.|:.||||||||:|::|:..::||.|||||||||:|||||.||||||||||||:|.|:|||
 Frog     1 MNRYTTMKQLGDGTYGSVLMGRSNESGELVAIKRMKRKFYSWEECMNLREVKSLKKLNHANVVKL 65

  Fly    66 KEVIRENDTLYFVFEYMKENLYQMIKDRDTHL-PEPELKSILFQVLTGLAFMHRHGFFHRDLKPE 129
            ||||||||.|:||||||||||||::|||:..: .|.|:::|:||||:||||:|:|||||||:|||
 Frog    66 KEVIRENDQLFFVFEYMKENLYQLMKDRENKMFTENEIRNIMFQVLSGLAFVHKHGFFHRDMKPE 130

  Fly   130 NLLCSGPDLIKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELY 194
            ||||.||:|:|||||||.||:||:||:||||||||||||||||.|::|.|.||:||:|.||||||
 Frog   131 NLLCMGPELVKIADFGLVRELRSQPPYTDYVSTRWYRAPEVLLRSSSYSSPIDIWAVGSIMAELY 195

  Fly   195 TFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFRYPDCIKVPLSSVVSRCSQNGLD 259
            |.||||||:|||||:||||.|||||.|:|||:||:||:.::||:|.|:.:.|.:::...|::.|.
 Frog   196 TLRPLFPGTSEVDQIFKICQVLGTPKKNDWPEGYQLAASMNFRFPQCVPINLKTLIPNASEDALS 260

  Fly   260 LLEDMLAYDPDKRPTAQQSLKYPYFHALKRISPTAATKANVRLNSKYAASNGHPVQSVSNNVLPV 324
            |:.|.:.:||.|||||.|:|::|||...:.:.|                    |||.|...
 Frog   261 LMRDTMQWDPKKRPTASQALRHPYFQVGQALGP--------------------PVQYVEQK---- 301

  Fly   325 QEKLQAVTELLHQTNNNMNSHSNLGKNNNLAPKNGGVPRKYQP----KLSFLTTSEMGAGSHADS 385
                                     |..|.|||    |::.:|    |:...::||:...|..|:
 Frog   302 -------------------------KPLNKAPK----PQEPRPIYVTKMQSSSSSEILEKSSPDT 337

  Fly   386 SSLVGGATVDGVPVPQHQNGGESINDIYLNRNISQLFGLPAGPQHQQQQQVHHPNVSFSTTSSRN 450
            .... ...:..:.|||      |.:||.          ||:     :.|||..|::| .|.|.:.
 Frog   338 PPAT-NRPLQQIQVPQ------STDDIQ----------LPS-----KTQQVVLPSIS-KTISPKP 379

  Fly   451 AGAIYVNGSHLSYDTANMNAKNNAKFVVGASNGGYYVPVARPSLLGPDAKVYNVFSKVSASQAPP 515
            .    .||...|..:.....:...:.||..|..                ::...|. :|.|:.|.
 Frog   380 V----ANGPQTSAVSIKHGRRRWGQSVVKDSWD----------------EIDTDFG-ISYSKKPT 423

  Fly   516 SLIVRQPQLQPEVAPAPMRLSGRSRAAAAVQDPKMGALKSDDLDLILGSKLKTSAKRQRNAKANI 580
            ..:.::.  :||.:     |.|.|...:.|.:.|..:        |:|.| :|...:..:||.:.
 Frog   424 MALAKEN--KPEDS-----LFGLSDPISIVDENKGSS--------IVGMK-RTDTSQTTSAKQHY 472

  Fly   581 LLEDLF---------GQLSMDSDSDGKYPH-----TVPPTQQAKSGKTSTGGHGAGARERDLFGE 631
            |.:..:         |.:|  ::.|||:..     |..|.....:|...:..:|||.. ....|.
 Frog   473 LRQSRYLPGMNPKNAGLIS--ANKDGKHATWNSALTTKPLGPIGAGLGFSKANGAGIL-GGFIGP 534

  Fly   632 SYLPR----PGLRKKATQSSLEVNNGSHADSLAP-NAQKEKPAVASS 673
            ||...    |...||      ||.:......||| .|....|.::.:
 Frog   535 SYNSPGGYIPSFNKK------EVGSAGQRIQLAPIGAATTAPVISDA 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	189/280 (68%)
mak	XP_012820404.1	STKc_MAK_like	4..285	CDD:270824	189/280 (68%)