Protein Alignment CG42366 and CDK16

DIOPT Version :10

• Sequence 1: NP_723501.2
• Gene: CG42366 / 34319
• FlyBaseID: FBgn0259712
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_011542222.1
• Gene: CDK16 / 5127
• HGNCID: 8749
• Length: 571
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 116/289 - (40%)
• Similarity: 169/289 - (58%)
• Gaps: 3/289 - (1%)

  Fly     1 MNRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLSHPNIVKL 65
            :..||.|.:||:|||.||..|:.|.|...||:|.::.::........:|||..||.|.|.|||.|
Human   236 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTL 300

  Fly    66 KEVIRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRDLKPEN 130
            .::|....:|..||||:.::|.|.:.|....:....:|..|||:|.|||:.||....||||||:|
Human   301 HDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQN 365

  Fly   131 LLCSGPDLIKIADFGLAREIRSRP--PFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAEL 193
            ||.:....:|:||||||| .:|.|  .:::.|.|.|||.|::||.||:|.:.||:|.:|||..|:
Human   366 LLINERGELKLADFGLAR-AKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEM 429

  Fly   194 YTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFRYPDCIKVPLSSVVSRCSQNGL 258
            .|.|||||||:..:||..|..:||||.::.||..........:.||......|.|...|...:|.
Human   430 ATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA 494

  Fly   259 DLLEDMLAYDPDKRPTAQQSLKYPYFHAL 287
            |||..:|.::...|.:|:.::|:|:|.:|
Human   495 DLLTKLLQFEGRNRISAEDAMKHPFFLSL 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	114/281 (41%)
CDK16	XP_011542222.1	STKc_PCTAIRE1	236..532	CDD:270854	116/289 (40%)