Protein Alignment CG42366 and CDK20

DIOPT Version :10

• Sequence 1: NP_723501.2
• Gene: CG42366 / 34319
• FlyBaseID: FBgn0259712
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_047279074.1
• Gene: CDK20 / 23552
• HGNCID: 21420
• Length: 364
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 116/351 - (33%)
• Similarity: 177/351 - (50%)
• Gaps: 50/351 - (14%)

  Fly     1 MNRYITLTQLGDGTYGTVVLGQRKD-------------TGEKVAIKRMK-RKYYSWEEAMNLREV 51
            |::|..|.::|:|.:|.|...:..:             |||.||:|::. |:.........|||:
Human     1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQALREI 65

  Fly    52 KSLKKL-SHPNIVKLKEVIRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAF 115
            |:|::: .:..:|:||.|..........||:|..:|.::::.....|.:.::||.|..:|.|:||
Human    66 KALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAF 130

  Fly   116 MHRHGFFHRDLKPENLLCSGPDLIKIADFGLAREIR---SRPPFTDYVST-----RWYRAPEVLL 172
            .|.:...||||||.|||.|....:|||||||||...   || .:|..|:|     |||||||:|.
Human   131 CHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSR-LYTHQVATSPLPRRWYRAPELLY 194

  Fly   173 HSTNYGSTIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFR 237
            .:..|...:|||::||||.||....|||||.::::||..:..:||||:...||:...|.......
Human   195 GARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKIS 259

  Fly   238 YPDCIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYFHALKRISPTAATKANVRL 302
            :.:.:.:||..|:...|...||||...|.|.|.:|..|.::|.:.||.       ||...|
Human   260 FKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFF-------TAPLPA---- 313

  Fly   303 NSKYAASNGHPVQSVSNNVLPVQEKL 328
                     ||.:      ||:.::|
Human   314 ---------HPSE------LPIPQRL 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	105/302 (35%)
CDK20	XP_047279074.1	STKc_CCRK	3..307	CDD:270826	106/304 (35%)