Protein Alignment CG42366 and cdk-5

DIOPT Version :10

• Sequence 1: NP_723501.2
• Gene: CG42366 / 34319
• FlyBaseID: FBgn0259712
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_499783.1
• Gene: cdk-5 / 176774
• WormBaseID: WBGene00000407
• Length: 292
• Species: Caenorhabditis elegans
• Alignment Length: 299
• Identity: 110/299 - (36%)
• Similarity: 169/299 - (56%)
• Gaps: 28/299 - (9%)

  Fly     1 MNRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAM---NLREVKSLKKLSHPNI 62
            |..|..:.::|:||||||...:.|::||.||:||::..  ..:|.:   .|||:..|::|.|.|:
 Worm     1 MLNYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLD--DDDEGVPSSALREICILRELKHRNV 63

  Fly    63 VKLKEVIRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRDLK 127
            |:|.:|:...:.|..||||..::|.:.....:.::.....:|::.|:|.||:|.|.|...|||||
 Worm    64 VRLYDVVHSENKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHVLHRDLK 128

  Fly   128 PENLLCSGPDLIKIADFGLAR----EIRSRPPFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGC 188
            |:|||.:....:|:|||||||    .:|.   |:..|.|.|||.|:||..:..|.::||:|:.||
 Worm   129 PQNLLINTNGTLKLADFGLARAFGVPVRC---FSAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGC 190

  Fly   189 IMAELYTF-RPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFRYPDCIKVPL------ 246
            |.||:... ||||||:...|||.:|...||:|.:|:||...:|        ||....|:
 Worm   191 IFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQL--------PDYKPYPIYHPTLT 247

  Fly   247 -SSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYF 284
             |.:|...:..|.|||:.:|..:|..|..|..:|::.||
 Worm   248 WSQIVPNLNSRGRDLLQKLLVCNPAGRIDADAALRHAYF 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	107/294 (36%)
cdk-5	NP_499783.1	STKc_CDK5	3..286	CDD:143344	107/295 (36%)