Protein Alignment CG42366 and cdk-12

DIOPT Version :10

• Sequence 1: NP_723501.2
• Gene: CG42366 / 34319
• FlyBaseID: FBgn0259712
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_001367220.1
• Gene: cdk-12 / 175559
• WormBaseID: WBGene00007135
• Length: 734
• Species: Caenorhabditis elegans
• Alignment Length: 444
• Identity: 137/444 - (30%)
• Similarity: 225/444 - (50%)
• Gaps: 65/444 - (14%)

  Fly     1 MNRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAM---NLREVKSLKKLSHPNI 62
            :..|..|.|:|:||||.|.......|||:||:||::.:  :.:|..   .:||:|.|::|.|.||
 Worm   308 LTHYTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLE--NEKEGFPITAIREIKILRQLHHKNI 370

  Fly    63 VKLKEVI----------RENDTLYFVFEYMKENLYQMIKDRD-THLPEPELKSILFQVLTGLAFM 116
            |:|.:::          |.....|.||||:..:|..:::.:: ....:.::.|:..|:|.|||::
 Worm   371 VRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLLEGLAYI 435

  Fly   117 HRHGFFHRDLKPENLLCSGPDLIKIADFGLAR--EIRSRPPFTDYVSTRWYRAPEVLLHSTNYGS 179
            |..||.|||:|..|:|.:....:||||.||||  |..|| .:|:.|.|.|||.||:||....||.
 Worm   436 HNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESR-LYTNRVITLWYRPPELLLGDERYGP 499

  Fly   180 TIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFR----YPD 240
            .||:|:.||::.||:|.:|||.|::|..||..|..|.|:|:.|:||:...|.....||    |..
 Worm   500 AIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELVGWNTFRMKRTYQR 564

  Fly   241 CIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYFHALKR--ISP----------- 292
            .|:.....::.|   ..:|||:.||..:|:||.:|:::|.:|:..:|:.  :.|
 Worm   565 RIREEFEHIMPR---EAVDLLDKMLTLNPEKRISAKEALNHPWIRSLEHTTVQPLKLPQHQDCHE 626

  Fly   293 --TAATKANVRL--NSKYAASNGHPVQSVSN----NVLPVQEKLQAVTELLHQTNNNMNSHSNLG 349
              :...|.:.||  .::.::.:||.:::.|:    ...|.|.. ...|:....:|::.:.|.:..
 Worm   627 MWSKKQKKSARLGRQAEGSSGSGHSIRATSHPRVFEAAPTQPS-TTTTKSNGSSNHHHHHHHSHH 690

  Fly   350 KNNNLAPKNGGVPRKYQPKLSFLTTSEMGAGSHADSSSLVGGATVDGVPVPQHQ 403
            ..::|.|..|..|....|.....:||.   .:|.              ||||.|
 Worm   691 HASSLPPSGGHAPPPPPPPTQASSTSH---NNHQ--------------PVPQSQ 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	111/299 (37%)
cdk-12	NP_001367220.1	STKc_CDK12	303..605	CDD:270847	111/302 (37%)