Protein Alignment CG42366 and Mak

DIOPT Version :10

• Sequence 1: NP_723501.2
• Gene: CG42366 / 34319
• FlyBaseID: FBgn0259712
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_006516931.1
• Gene: Mak / 17152
• MGIID: 96913
• Length: 647
• Species: Mus musculus
• Alignment Length: 614
• Identity: 256/614 - (41%)
• Similarity: 349/614 - (56%)
• Gaps: 112/614 - (18%)

  Fly     1 MNRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLSHPNIVKL 65
            ||||.|:.||||||||:|::|:..::||.|||||||||:|||:|.||||||||||||:|.|::||
Mouse     1 MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKL 65

  Fly    66 KEVIRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRDLKPEN 130
            ||||||||.||||||||||||||::|||:...||..:::|::|:|.||||:|:|||||||:||||
Mouse    66 KEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPEN 130

  Fly   131 LLCSGPDLIKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYT 195
            |||.||:|:||||||||||:||:||:||||||||||||||||.|:.|.|.||:||:|.|||||||
Mouse   131 LLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYT 195

  Fly   196 FRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFRYPDCIKVPLSSVVSRCSQNGLDL 260
            |||||||:||||::||||.|||||.|.|||:||:|||.::||:|.||.:.|.:::...|...:.|
Mouse   196 FRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSEAIQL 260

  Fly   261 LEDMLAYDPDKRPTAQQSLKYPYF----------HAL-------KRISPTAATKANVRLNSKYAA 308
            :.:||.:||.|||||.|:||:|||          |.|       |::.|.....::...:.|...
Mouse   261 MTEMLNWDPKKRPTASQALKHPYFQVGQVLGSSAHHLDTKQTLHKQLQPLEPKPSSSERDPKPLP 325

  Fly   309 S------------NGH-PVQSV---SNNVL---PVQEKLQAVTELLHQT---NNNMNSHSNLGKN 351
            :            .|| |:|::   .|.|.   |.|:..|...:.:..:   ...:||.|.||
Mouse   326 NILDQPAGQPQPKQGHQPLQTIQPPQNTVTHPPPKQQGHQKPPQTMFPSIIKTIPVNSVSTLG-- 388

  Fly   352 NNLAPKNGGVPRKYQPKLSFLTTS------EMGAGSHADSSSLVGGATV----------DGVPVP 400
                  :.|..|::...:.....|      ::|| ||:...|:......          .|:||.
Mouse   389 ------HKGARRRWGQTVFKSGDSCDDIEDDLGA-SHSKKPSMEACKEKKKESPFRFPDSGLPVS 446

  Fly   401 QHQNGGESINDIYLNRNISQLFGLPAGPQHQQQQQVHHPNVSFSTTSSRNAGAIYVNGSHLSYDT 465
            .|..|.        |||:           |........||:|.::|:.:    .|:..|..   .
Mouse   447 NHFKGE--------NRNL-----------HASVSLKSDPNLSTASTAKQ----YYLKQSRY---L 485

  Fly   466 ANMNAKNNAKFVVGASNGGYYVPVARPSLLGPDAKVYN----VFSKVSASQAPPSLIVRQPQLQP 526
            ..:|.| |...|.|                |.|...::    :|.| |.......|..::...:.
Mouse   486 PGVNPK-NVSLVAG----------------GKDINSHSWNNQLFPK-SLGSMGADLSFKRSNAED 532

  Fly   527 EVAPAPMRLSGRSRAAAAVQDPKMGALKS 555
            .:......||...::|..::||:.|.|.|
Mouse   533 SIIKPIENLSCTGKSAEQLEDPQAGNLGS 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	190/279 (68%)
Mak	XP_006516931.1	STKc_MAK_like	4..284	CDD:270824	190/279 (68%)