Protein Alignment CG42366 and MAPK14

DIOPT Version :10

• Sequence 1: NP_723501.2
• Gene: CG42366 / 34319
• FlyBaseID: FBgn0259712
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_011512612.2
• Gene: MAPK14 / 1432
• HGNCID: 6876
• Length: 401
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 102/274 - (37%)
• Similarity: 153/274 - (55%)
• Gaps: 26/274 - (9%)

  Fly    26 TGEKVAIKRMKRKYYSWEEA-MNLREVKSLKKLSHPNIVKLKEV------IRENDTLYFVFEYMK 83
            ||.:||:|::.|.:.|...| ...||::.||.:.|.|::.|.:|      :.|.:.:|.|...|.
Human    87 TGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMG 151

  Fly    84 ENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRDLKPENLLCSGPDLIKIADFGLAR 148
            .:|..::|.:  .|.:..::.:::|:|.||.::|.....||||||.||..:....:||.||||||
Human   152 ADLNNIVKCQ--KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR 214

  Fly   149 EIRSRPPFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKIC 213
              .:....|.||:||||||||::|:..:|..|:|:|::|||||||.|.|.||||:..:|||..|.
Human   215 --HTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIL 277

  Fly   214 SVLGTPDKDDWPDGYRLASMIHF----RYPDCI----KVPLSSVVSRCSQNGLDLLEDMLAYDPD 270
            .::|||       |..|...|..    .|...:    |:..::|....:...:||||.||..|.|
Human   278 RLVGTP-------GAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSD 335

  Fly   271 KRPTAQQSLKYPYF 284
            ||.||.|:|.:.||
Human   336 KRITAAQALAHAYF 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	100/272 (37%)
MAPK14	XP_011512612.2	Protein Kinases, catalytic domain	57..391	CDD:473864	102/274 (37%)