Protein Alignment CG42366 and CDK7

DIOPT Version :10

• Sequence 1: NP_723501.2
• Gene: CG42366 / 34319
• FlyBaseID: FBgn0259712
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_001790.1
• Gene: CDK7 / 1022
• HGNCID: 1778
• Length: 346
• Species: Homo sapiens
• Alignment Length: 371
• Identity: 134/371 - (36%)
• Similarity: 198/371 - (53%)
• Gaps: 47/371 - (12%)

  Fly     3 RYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYS-WEEAMN---LREVKSLKKLSHPNIV 63
            ||..|..||:|.:.||...:.|:|.:.||||::|..:.| .::.:|   |||:|.|::||||||:
Human    11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNII 75

  Fly    64 KLKEVIRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRDLKP 128
            .|.:.......:..||::|:.:|..:|||....|....:|:.:...|.||.::|:|...||||||
Human    76 GLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKP 140

  Fly   129 ENLLCSGPDLIKIADFGLAREIRS-RPPFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAE 192
            .|||.....::|:||||||:...| ...:|..|.||||||||:|..:..||..:|:||:|||:||
Human   141 NNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAE 205

  Fly   193 LYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFR-YPDCIKVPLSSVVSRCSQN 256
            |....|..||.|::|||.:|...||||.::.|||...|...:.|: :|.   :||..:.|....:
Human   206 LLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPG---IPLHHIFSAAGDD 267

  Fly   257 GLDLLEDMLAYDPDKRPTAQQSLKYPYFHALKRISPTAATKANVRLNSKYAASNGHPVQSV---S 318
            .|||::.:..::|..|.||.|:||..||.  .|..||...:. .|.|.        ||:::   |
Human   268 LLDLIQGLFLFNPCARITATQALKMKYFS--NRPGPTPGCQL-PRPNC--------PVETLKEQS 321

  Fly   319 NNVLPVQEKLQAVTELLHQTNNNMNSHSNLGKNNNLAPKNGGVPRK 364
            |..|.::.|.   ||.|.|                     ||:|:|
Human   322 NPALAIKRKR---TEALEQ---------------------GGLPKK 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	112/285 (39%)
CDK7	NP_001790.1	STKc_CDK7	11..308	CDD:270833	118/302 (39%)