Protein Alignment CG42366 and cdk13

DIOPT Version :10

• Sequence 1: NP_723501.2
• Gene: CG42366 / 34319
• FlyBaseID: FBgn0259712
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_002940845.2
• Gene: cdk13 / 100489599
• XenbaseID: XB-GENE-6040279
• Length: 1391
• Species: Xenopus tropicalis
• Alignment Length: 662
• Identity: 168/662 - (25%)
• Similarity: 271/662 - (40%)
• Gaps: 179/662 - (27%)

  Fly    10 LGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAM---NLREVKSLKKLSHPNIVKLKEVI-- 69
            :|:||||.|...:.|||||.||:|:::..  :.:|..   .:||:|.|::|:|.:|:.:||::
 Frog   604 IGEGTYGQVYKAKDKDTGEMVALKKVRLD--NEKEGFPITAIREIKILRQLNHQSIINMKEIVTD 666

  Fly    70 --------RENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRDL 126
                    ::....|.|||||..:|..:::....|..|..:||.:.|::.||.:.|:..|.|||:
 Frog   667 KEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNEHHIKSFMRQLMEGLDYCHKRNFLHRDI 731

  Fly   127 KPENLLCSGPDLIKIADFGLAREIRSRP--PFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCI 189
            |..|:|.:....||:|||||||...|..  |:|:.|.|.|||.||:||....|...||:|:.|||
 Frog   732 KCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYSPAIDVWSCGCI 796

  Fly   190 MAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFRYPDCIKVPLSSVVSRCS 254
            :.||:|.:|:|..:.|:.||..|..:.|:|....|              ||.||:|..:.:....
 Frog   797 LGELFTKKPIFQANQELAQLELISRMCGSPCPAVW--------------PDVIKLPYFNTMKPKK 847

  Fly   255 Q--------------NGLDLLEDMLAYDPDKRPTAQQSLKYPYFHALKRISPTAATKANVRLNSK 305
            |              ..|||.:.|||.||:||.||:|:|...:   |:.:.|:..|..:
 Frog   848 QYRRKLREEFVFIPNAALDLFDHMLALDPNKRCTAEQALLCEF---LRDVDPSKMTPPD------ 903

  Fly   306 YAASNGHPVQSVSNNVLPVQEKLQAVTELLHQT-NNNMNSHSNLGKNNNL-APKNGGVPRKYQPK 368
                            ||:.:.       .|:. :........||..::| .||   ||||
 Frog   904 ----------------LPLWQD-------CHELWSKKRRRQKQLGMGDDLTVPK---VPRK---- 938

  Fly   369 LSFLTTSEMG---------AGSHADSSSLVGGATVDGVPVPQHQNGGESIND----IYLN----- 415
                 .|.:|         .|....|.....|....||..|   :.|:.:|.    |.||
 Frog   939 -----DSSLGMDDSRNSTPQGMQISSQLKTQGFPSVGVGNP---SSGQQLNHNEVAILLNLLKSQ 995

  Fly   416 -----RNISQLFGLPAGPQHQQQQQVHHPNVSFSTTSSRNAGAIYVNGSHLSYDTANMNAKNNAK 475
                 .:.:|:..:...|:.|||..    |::..      ||.:.|         .:..|:..|:
 Frog   996 TSVNMAHFAQVLNIKVNPETQQQLN----NINLP------AGILAV---------GDKQAEQRAE 1041

  Fly   476 FVVGASNGGYYVPVA-RPSLLGPDAKVYNVFSKVSASQAPPSLIVRQPQLQPEVAPAPMRLSGRS 539
                       :|:| :|.|                   ||...:...:...:|.||.::.:...
 Frog  1042 -----------IPLATQPEL-------------------PPIPHLPLTKTNTDVTPATVQSTFTF 1076

  Fly   540 RAAAAVQDPKM--------GALKSDDLDLILGSKLKTSAKRQRNAKANILLEDLFGQLSMDSDSD 596
            ..:..::|.::        |.:|....:|:...|...|.....|..    |.|...:....:...
 Frog  1077 LLSLLLKDQELKKKSDVTAGEVKEHMSELLCKPKRPPSPSPIDNCN----LGDHEVKQLQSTSLQ 1137

  Fly   597 GKYPHTVPPTQQ 608
            .:||..:||.|:
 Frog  1138 PEYPQILPPDQR 1149

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	106/302 (35%)
cdk13	XP_002940845.2	STKc_CDK12	590..891	CDD:270847	106/305 (35%)