Protein Alignment CG42366 and cdkl2

DIOPT Version :10

• Sequence 1: NP_723501.2
• Gene: CG42366 / 34319
• FlyBaseID: FBgn0259712
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_002938668.2
• Gene: cdkl2 / 100487310
• XenbaseID: XB-GENE-5959638
• Length: 565
• Species: Xenopus tropicalis
• Alignment Length: 613
• Identity: 170/613 - (27%)
• Similarity: 259/613 - (42%)
• Gaps: 130/613 - (21%)

  Fly     1 MNRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEE-----AMNLREVKSLKKLSHP 60
            |.:|..|..:|:|:||.|:..:.|:.|..||:|    |:...|:     .:.:||:|.||:|.|.
 Frog     1 MEKYENLGLVGEGSYGMVMKCRNKENGRIVAVK----KFLESEDDKMVKKIAMREIKLLKQLRHE 61

  Fly    61 NIVKLKEVIRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRD 125
            |:|.|.||.::....|.|||::...:...::.....|...:::..|||::.|:.|.|.|...|||
 Frog    62 NLVNLLEVCKKKKRWYLVFEFVDRTVLDDLEQFPNGLDFSKVRKYLFQIIRGIGFCHSHNIIHRD 126

  Fly   126 LKPENLLCSGPDLIKIADFGLAREIRS-RPPFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCI 189
            :||||:|.|...::|:.|||.||.:.. ...:||||:||||||||:|:....||..:|:||:|||
 Frog   127 IKPENILVSHSGIVKLCDFGFARTLAGPGEDYTDYVATRWYRAPELLVGDIKYGKAVDVWAIGCI 191

  Fly   190 MAELYTFRPLFPGSSEVDQLFKICSVLG--TPDKDD------------WPDGYRLASMIHFRYPD 240
            :.|:.|.:|||||.|::|||..|....|  ||...:            .|| .:.|..:.:|||
 Frog   192 VTEMLTAQPLFPGDSDIDQLHHIVKCQGNLTPRHQELFYRNPMFAGFSLPD-MKEAESLEWRYP- 254

  Fly   241 CIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYF--------------------- 284
                .||.::       |||.:..|..||||||.....|.:..|
 Frog   255 ----KLSPIM-------LDLAKSCLHIDPDKRPACMTLLLHELFTKDSFSERFSQEIRAKLQNLP 308

  Fly   285 --HAL--KRISPTAATKANVRLNSKYAASNGHPVQSVSNNVLPVQ-----------EKLQAVTEL 334
              ::|  |::......|.:..:.:|..|.......|....:.|.:           ||..|.:..
 Frog   309 KDNSLQSKKLKNHKKEKEDYAIENKTTAFQECNFDSKIKEIKPTKVKIIKTDMEKSEKSDAFSNS 373

  Fly   335 LHQTNNNMN---SHSNLGKNNNLAP--KNGGVPRKYQPKLSF-LTTSEMGAGSHADSSSLVGGAT 393
            .:.::.|.|   ||..|.:.:|...  |:.|:    .|.::: ||.......|:|.:.|.:|
 Frog   374 FYSSSTNQNKIASHVALKETSNSLDLHKSAGI----IPLINYNLTAISPYMNSNASTVSGIG--- 431

  Fly   394 VDGVPVPQHQN-GGESINDIYLNRNISQLFGLPAGPQHQQQQ----------QVHHPNVSFSTTS 447
                    |.| .||..:.:|  .|..:..|.||...|..|.          |.......||...
 Frog   432 --------HGNFRGEDKSKLY--SNSLKKSGKPATGSHYNQNLAPLVDKSPLQRSKKRWDFSKAE 486

  Fly   448 SRNAGAIYVNGSHL----SYDTANMNAKNNAKFVVGASNGGYYVPVARPSLLGPDAKV---YNVF 505
            .|.....|   |||    ..|...:....::|.....|.     ||..|.:  |...:   ||
 Frog   487 MRLPELHY---SHLPELKGTDCGTLFCAQSSKLTKKDSR-----PVHEPRI--PSLAISEPYN-- 539

  Fly   506 SKVSASQAPPSLIVRQPQLQPEVAPAPM 533
                ||.|.|.::....|..|:....|:
 Frog   540 ----ASMALPQVLGNSLQETPDANFPPV 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	108/299 (36%)
cdkl2	XP_002938668.2	STKc_CDKL2_3	2..287	CDD:270836	108/301 (36%)