Protein Alignment TbCMF46 and Ppp1r42

DIOPT Version :10

• Sequence 1: NP_609325.2
• Gene: TbCMF46 / 34318
• FlyBaseID: FBgn0032163
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_663730.1
• Gene: Ppp1r42 / 69312
• MGIID: 1921138
• Length: 357
• Species: Mus musculus
• Alignment Length: 370
• Identity: 87/370 - (23%)
• Similarity: 128/370 - (34%)
• Gaps: 119/370 - (32%)

  Fly    68 RITTMRLEFKNILRIDHLWMMPNLTKLCLNCNKIEVIEHLEMLTALKDLNLSFNYITRIENLEKL 132
            :||.:....:||..||.|.:..||:.|.|..|:|..:.:|...|.|..|.|..|.|:.||||..|
Mouse    29 KITHINFSDRNIDSIDDLSLCRNLSVLYLYDNRISQVTNLNYTTNLTHLYLQNNCISCIENLSSL 93

  Fly   133 VKLEKLSLFSNRIRKIENIHTLQ------------------------------NLVILSIGNNLI 167
            .|||||.|..|.|..||.:..|:                              :|..|:|.||.|
Mouse    94 KKLEKLYLGGNYIAVIEGLEGLEELRELHVESQRLPLGEKLLFDPRTLRSLAKSLSTLNISNNNI 158

  Fly   168 DTVEGIE-------------RLRFVSSLKVL----------NLEGNPIAKQPDFPLSLYVIAILP 209
            |.::.:|             :|..|..|::|          :|.|||:..:|.:...|  |....
Mouse   159 DDIKDLEILENLNHLIAVDNQLMHVKDLELLLKKLMKLWKMDLNGNPVCLKPKYRDKL--ILTSK 221

  Fly   210 QLNYYEYVFIKTETRE---------EAQKRFYRELREIEDKQEREIQGLETEAREMAEADRLASS 265
            .|.:.:...||...|:         :|:|...:.....||.....|...||
Mouse   222 SLEFLDGKEIKDMERQFLMNWKASKDAKKISKKRRSRSEDASNSYISNFET-------------- 272

  Fly   266 FVEHL----------------DGMQLYDSLWRDDEDGRILMLVGAPAQELCEEYSKDVYELTQQI 314
             |.|:                ..:|.|              ||...|...|.:  :|...:|:.|
Mouse   273 -VHHIVPVYYPQVGKPKVIFFSDVQRY--------------LVHGNASSKCSQ--EDKTTITEDI 320

  Fly   315 YRLGLERFGERDEEIRDFNANLHEGQEELQAQGQRQIEDFLEYKE 359
            ..|.|     ::.|......::||..   ..|..:..|:..|.||
Mouse   321 GNLSL-----KESESSLTKNDIHEPH---LLQNPKVKENLSEKKE 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TbCMF46	NP_609325.2	PPP1R42	66..>190	CDD:455733	49/174 (28%)
		leucine-rich repeat	69..90	CDD:275378	7/20 (35%)
		leucine-rich repeat	91..112	CDD:275378	6/20 (30%)
		leucine-rich repeat	113..134	CDD:275378	10/20 (50%)
		leucine-rich repeat	135..156	CDD:275378	10/50 (20%)
		leucine-rich repeat	157..181	CDD:275378	10/36 (28%)
		SMC_prok_B	225..>530	CDD:274008	28/160 (18%)
Ppp1r42	NP_663730.1	PPP1R42	27..246	CDD:411060	59/218 (27%)
		LRR 1	29..50		7/20 (35%)
		leucine-rich repeat	31..51	CDD:275380	6/19 (32%)
		LRR 2	51..72		7/20 (35%)
		LRR 3	73..94		9/20 (45%)
		leucine-rich repeat	74..95	CDD:275380	10/20 (50%)
		LRR 4	95..116		10/20 (50%)
		leucine-rich repeat	96..147	CDD:275380	10/50 (20%)
		LRR 5	117..138		0/20 (0%)
		LRR 6	147..168		8/20 (40%)
		leucine-rich repeat	148..169	CDD:275380	8/20 (40%)
		LRR 7	169..190		3/20 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	329..357		6/30 (20%)