Protein Alignment TbCMF46 and lrrcc1

DIOPT Version :10

• Sequence 1: NP_609325.2
• Gene: TbCMF46 / 34318
• FlyBaseID: FBgn0032163
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_690381.2
• Gene: lrrcc1 / 561887
• ZFINID: ZDB-GENE-041111-207
• Length: 997
• Species: Danio rerio
• Alignment Length: 600
• Identity: 115/600 - (19%)
• Similarity: 219/600 - (36%)
• Gaps: 165/600 - (27%)

  Fly    77 KNILRIDHLWMMPNLTKLCLNCNKIEVIEHLEMLTALKDLNLSFNYITRIENLEKLVKLEKLSLF 141
            |:|..:..:.:.|:::.|.|:||::..||.|.....::.|:||.|:|.|||.|..|..|..|:|.
Zfish    11 KDISSLLEVSLNPSISSLNLHCNRLTKIEGLTTAWHIRHLDLSSNHICRIEGLASLSSLRTLNLS 75

  Fly   142 SNRIRKIENIHTLQNLVILSIG---------------------------------NNLIDTVEGI 173
            .|.|.|:|.:..|.||..|::.                                 |:|:..:.|:
Zfish    76 CNLITKVEGLDGLTNLTRLNLAYNQINDLTGLLYLHGANYKLKYLQLHSNRLDSMNHLLQCMVGL 140

  Fly   174 ERLRFVSSLKVLNLEG--NPIAKQ------------------------------PDFPLSLYVIA 206
            :.|::::    |:.:|  ||:.|.                              .|.|:.
Zfish   141 QNLKYIT----LSKDGAENPVCKMIGYREMVLQCLHQVTTLDGVDRMGNTCPLAEDSPMD----- 196

  Fly   207 ILPQLNYYEYVFIKTETR-----------------EEAQKRF-YRELREIEDKQERE--IQGLET 251
             :|.|..:....|.::|.                 :|...:| .|..:...:.||.|  |:.||.
Zfish   197 -VPGLEDFLEFLISSDTSVNGELAKSDAPLTTPRIDEVLTQFRQRGGKASTENQENEQRIKKLEQ 260

  Fly   252 EA----REMAEADRLASSFVEHLDGMQL------------YDSLWRDDEDGRILMLV-GAPAQEL 299
            :.    :::.|:||:.|:.......|:.            .||...:....|:|... |:..::|
Zfish   261 QVSHLIQKVPESDRVNSNSTAQPSVMRKAKRDTDQTSESECDSGKENQRHSRVLFHPRGSAGKKL 325

  Fly   300 CEE---YSKDVYELTQQIYRLGLERFGERDEEIR-----DFNANLHEG----QEELQAQGQRQIE 352
            .::   ...|...:||:.....|.....|...|:     |.:.::..|    :..|::.||.|.|
Zfish   326 SKDTKPKQSDCVAITQKQRSTKLTVCPRRSTSIQSSESADTSESVKRGPKIIKSGLKSSGQSQEE 390

  Fly   353 DFLEYKERIFDEMRLKWRELDQRDDDLEQLQAQLDTLTANFEDSLNELWESLMAQELHLHEAVED 417
            .:....|....|...:|:        .||...:|.....|.:...:| .:.|.:..||..:.:::
Zfish   391 TYKAIVEERDQERERRWK--------AEQAAKKLTEQVKNLQTRASE-EKDLQSLALHTTDRLKE 446

  Fly   418 STLKFNRKISDLMSNFVEQAQVIFLQLRDLCSYFADNMTDIVNQFLSTKLARNELNTIPEELKQC 482
            ..||             |::....||.|         :.::..::.|......::....|:.|:.
Zfish   447 MLLK-------------ERSDRAGLQTR---------LQELEERYRSAVEQLEQVRNREEQHKRA 489

  Fly   483 VDDREAVLQLVEGMRTTHTSRVDKREDRLAQRSRQFIDDMITNLNNKEVDRHRAKILEINSFMEM 547
            :...|..:...|.:|....:...||...|..::..|         .:||:..||...:....::.
Zfish   490 LCILEDSMSQAEALRVQQRAEEMKRTQELENKASAF---------KREVEILRASSRQHKEKLQQ 545

  Fly   548 MTEALANLPGELHQE 562
            :.|.||:.. |:|::
Zfish   546 LHELLASRE-EMHRK 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TbCMF46	NP_609325.2	PPP1R42	66..>190	CDD:455733	37/147 (25%)
		leucine-rich repeat	69..90	CDD:275378	2/12 (17%)
		leucine-rich repeat	91..112	CDD:275378	7/20 (35%)
		leucine-rich repeat	113..134	CDD:275378	10/20 (50%)
		leucine-rich repeat	135..156	CDD:275378	8/20 (40%)
		leucine-rich repeat	157..181	CDD:275378	6/56 (11%)
		SMC_prok_B	225..>530	CDD:274008	60/336 (18%)
lrrcc1	XP_690381.2	PPP1R42	6..181	CDD:455733	40/173 (23%)
		leucine-rich repeat	25..46	CDD:275378	7/20 (35%)
		leucine-rich repeat	47..68	CDD:275378	10/20 (50%)
		leucine-rich repeat	69..90	CDD:275378	8/20 (40%)
		leucine-rich repeat	91..116	CDD:275378	2/24 (8%)
		leucine-rich repeat	117..129	CDD:275378	0/11 (0%)
		PTZ00121	<353..921	CDD:173412	45/247 (18%)