Protein Alignment TbCMF46 and Lrrc61

DIOPT Version :10

• Sequence 1: NP_609325.2
• Gene: TbCMF46 / 34318
• FlyBaseID: FBgn0032163
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_808404.2
• Gene: Lrrc61 / 243371
• MGIID: 2652848
• Length: 259
• Species: Mus musculus
• Alignment Length: 278
• Identity: 61/278 - (21%)
• Similarity: 104/278 - (37%)
• Gaps: 87/278 - (31%)

  Fly    51 KKGEARRL---------HQLEPVVYDRITTMRLEFKNILRIDHLWMMPNLTKLCLNCNKIEVIEH 106
            |.|||..|         |..| ...|.|..::|....::.:..|..       |||
Mouse     7 KPGEAEALSITPQLLKSHSGE-FALDSILLLKLRGLGVVDLGCLGE-------CLN--------- 54

  Fly   107 LEMLTALKDLNLSFNYITRIENLEKLVKLEKLSLFSNRIRKIENIHTLQNLVILSIGNNLIDTVE 171
                  |:.|:||.|.:|.:..|..|.:|..|::.:||:..:|.:...:||..|:...||:.|..
Mouse    55 ------LEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLAACENLQSLNAAGNLLTTPG 113

  Fly   172 GIERLRFVSSLKVLNLEGNPIAKQPDFPL----SLYVIA--ILPQL------------------- 211
            .::.|..:.:|:.|.|. :|:|:..: ||    |.:.:.  :||.|
Mouse   114 QLQCLAGLQALEHLRLR-DPLARLSN-PLCANASYWAVVQELLPGLKVIDGERVSGRGSELYQLC 176

  Fly   212 --------------------------NYYEYVFIKTET-REEAQKRFYRELREIEDKQEREIQGL 249
                                      .|:|...|::.: .|||.::|...|:|..| .:|:....
Mouse   177 RDLDSSLRSGSSPGPRAIEAQPWVEPGYWESWPIRSSSILEEACRQFQDTLQECLD-LDRQASDS 240

  Fly   250 ETEAREMAEADRLASSFV 267
            ..:|::........||||
Mouse   241 LAQAQQALSPAETTSSFV 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TbCMF46	NP_609325.2	PPP1R42	66..>190	CDD:455733	30/123 (24%)
		leucine-rich repeat	69..90	CDD:275378	3/20 (15%)
		leucine-rich repeat	91..112	CDD:275378	3/20 (15%)
		leucine-rich repeat	113..134	CDD:275378	8/20 (40%)
		leucine-rich repeat	135..156	CDD:275378	5/20 (25%)
		leucine-rich repeat	157..181	CDD:275378	6/23 (26%)
		SMC_prok_B	225..>530	CDD:274008	13/43 (30%)
Lrrc61	NP_808404.2	LRR	<49..>131	CDD:443914	27/104 (26%)
		LRR 1	54..75		8/35 (23%)
		leucine-rich repeat	55..76	CDD:275380	8/20 (40%)
		LRR 2	76..97		5/20 (25%)
		leucine-rich repeat	77..98	CDD:275380	5/20 (25%)
		LRR 3	98..119		6/20 (30%)
		leucine-rich repeat	99..123	CDD:275380	6/23 (26%)