Protein Alignment TbCMF46 and T05H4.3

DIOPT Version :10

• Sequence 1: NP_609325.2
• Gene: TbCMF46 / 34318
• FlyBaseID: FBgn0032163
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001343670.1
• Gene: T05H4.3 / 188149
• WormBaseID: WBGene00020266
• Length: 1150
• Species: Caenorhabditis elegans
• Alignment Length: 600
• Identity: 117/600 - (19%)
• Similarity: 213/600 - (35%)
• Gaps: 153/600 - (25%)

  Fly    22 LRGFLEEINCPEPGIIDRQMIETAYLEEGKKGEARRLHQLEPVVYDRITTMRLEFKNILRIDHLW 86
            ||.|.::|.|.:|                       |.::.|.: :.:.......|::..:||
 Worm    72 LRLFGQQITCLKP-----------------------LGEVAPTL-EELWVCEGAVKDLAGVDH-- 110

  Fly    87 MMPNLTKLCLNCNKIEVIEHLEMLTALKDLNLSFNYITRIENLEKLVKLEKLSLFSNRIRK--IE 149
             ...|.||.|..|.||....|..||.|:.||::.|.:..:..|..:..|..|||..|:::.  :.
 Worm   111 -CIRLKKLFLYDNAIEDASCLCALTNLQYLNIASNKLKSLTFLRDMKDLTNLSLADNKMKDSVVA 174

  Fly   150 NIHTLQNLVILSIGNNLIDTVEGIERLRFVSSLKVLNLEGNPIAKQPDFPLSLYVIAILPQLNYY 214
            .....:::..|.|..|...:...:..|..:|||:.|||:  |:..:.....:|:...|.....:.
 Worm   175 TAIWPESIQHLDISANCFSSNRALFSLTILSSLRSLNLD--PVISKSTVAPNLFFAWIAHSFRFI 237

  Fly   215 EYV--------FIKTETREEAQKRFYRELREIEDKQEREIQGLETEAREMAEADR----LASSFV 267
            |.:        |:.| .|..|...:..:|.::....|:.::.|....:...:.:.    ||.:..
 Worm   238 ESLDDDPITESFVPT-YRPMADTIYAEKLAKLAKADEKYLKDLRMAEKHSGKIENRLACLAEALT 301

  Fly   268 EHLDGMQLYDSLWRDDEDGRILMLVGAPAQELCEEYSKDVYELTQQIYRLGLERFGERDEEIRDF 332
            .:.|.||..|:.                     :|..|.|:|:..           ...:.:::.
 Worm   302 AYKDAMQTKDAK---------------------KEIVKRVHEICV-----------SNSKAVKNI 334

  Fly   333 NANLHEGQEELQAQGQRQIEDFLEYKERIFDEMRLKWRELDQRDDDLEQLQAQLDTLTANFEDSL 397
            ..|.....|.:::..:.||...:|           ..:....||...|::  ...|.|.|:..|:
 Worm   335 KKNYTVLSEYIRSLSKYQISSDME-----------SCQTFQLRDGTAEEI--AFITQTLNYSCSM 386

  Fly   398 NELWESLMAQELHLHEAVEDSTLKF-------NRKISDLMSNF------------------VEQA 437
            ...:|.::.....|....::.|.:.       |.|:.||.:.|                  :...
 Worm   387 KNSYEIIVKSCSVLGNITKNETDRLFILEKDSNEKLFDLRTIFNLLDRFTRKDYTKHAVRLIRDF 451

  Fly   438 QVIFLQLRDLCSYFADNMTDIVNQFLSTKL-----ARNELNTIPEELKQCVDD-------REAVL 490
            :||..|.:|....|          ||...|     ||.....|.||.....:|       |...:
 Worm   452 EVIKKQEKDRTIIF----------FLPLVLSKMAAARGATKFIDEEGVSSSNDNLSWSDIRLLAV 506

  Fly   491 QLVE----GMRTTHTSR-VDKREDRLAQRSRQFIDDMITNLNNKEVDRHRAK----------ILE 540
            ..||    |..||...| :|:.|:...::.:: ::||...|:.|| :|||..          :..
 Worm   507 LAVEVQPIGQLTTDQLRHMDQFEESYNEQLKK-LNDMNIKLDVKE-ERHRRNEEPAETSIEAVSN 569

  Fly   541 INSFMEMMTEALANL 555
            ..|.:..:::.|||:
 Worm   570 QQSKIRKVSDVLANI 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TbCMF46	NP_609325.2	PPP1R42	66..>190	CDD:455733	33/125 (26%)
		leucine-rich repeat	69..90	CDD:275378	3/20 (15%)
		leucine-rich repeat	91..112	CDD:275378	9/20 (45%)
		leucine-rich repeat	113..134	CDD:275378	5/20 (25%)
		leucine-rich repeat	135..156	CDD:275378	5/22 (23%)
		leucine-rich repeat	157..181	CDD:275378	4/23 (17%)
		SMC_prok_B	225..>530	CDD:274008	60/350 (17%)
T05H4.3	NP_001343670.1	LRR	<62..>213	CDD:443914	40/167 (24%)
		leucine-rich repeat	69..91	CDD:275380	7/41 (17%)
		leucine-rich repeat	92..113	CDD:275380	3/24 (13%)
		leucine-rich repeat	114..135	CDD:275380	9/20 (45%)
		leucine-rich repeat	136..157	CDD:275380	5/20 (25%)
		leucine-rich repeat	158..181	CDD:275380	5/22 (23%)
		leucine-rich repeat	182..206	CDD:275380	4/23 (17%)
		PPP1R42	626..793	CDD:455733
		leucine-rich repeat	629..650	CDD:275380
		leucine-rich repeat	651..672	CDD:275380
		leucine-rich repeat	673..692	CDD:275380
		leucine-rich repeat	693..714	CDD:275380
		leucine-rich repeat	715..761	CDD:275380
		LRR	742..>1032	CDD:443914
		leucine-rich repeat	762..815	CDD:275380
		leucine-rich repeat	816..851	CDD:275380
		leucine-rich repeat	855..875	CDD:275380
		leucine-rich repeat	876..903	CDD:275380
		leucine-rich repeat	904..952	CDD:275380
		leucine-rich repeat	953..973	CDD:275380
		leucine-rich repeat	974..994	CDD:275380
		leucine-rich repeat	995..1019	CDD:275380