Protein Alignment TbCMF46 and Lrrc23

DIOPT Version :10

• Sequence 1: NP_609325.2
• Gene: TbCMF46 / 34318
• FlyBaseID: FBgn0032163
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_006505721.1
• Gene: Lrrc23 / 16977
• MGIID: 1315192
• Length: 370
• Species: Mus musculus
• Alignment Length: 264
• Identity: 66/264 - (25%)
• Similarity: 116/264 - (43%)
• Gaps: 36/264 - (13%)

  Fly    17 TEEEPLRGF--LEEINCPEPGIID----RQMIETAYLE-EGKKGEARRLHQLEPVVYDRITTMRL 74
            |:...||.:  |..::..|..|.|    ..:....:|: :|.:..:.|:::|.   |.:|.:  .
Mouse   109 TDISLLRSYIHLRYVDISENHITDISPLNSLTHLLWLKADGNQLRSARMNELP---YLQIAS--F 168

  Fly    75 EFKNILRIDHLWMMPNLTKLCLNCNKIEVIEHL--EMLTALKDLNLSFNYITRIENLEKLVKLEK 137
            .:..|:..:.:: .|.|..|.|..|:|..:..|  |.|::|..|.|..|.:...:.: .|.||:.
Mouse   169 SYNQIIDTEGIF-HPRLGSLDLKGNRIHQVTGLDPERLSSLHTLELRGNQLESTKGI-YLPKLKN 231

  Fly   138 LSLFSNRIRKIENIHTLQNLVILSIGNNLIDTVEGIERLRFVSSLKVLNLEGNPI------AKQP 196
            |.|..|.::|:|.:..|.||..|.:.:|.|:|:.|..  :.:.||:.|||..|.|      ||..
Mouse   232 LYLAQNLLKKVEGLENLSNLTTLHLRDNQIETLNGFS--QEMKSLQYLNLRSNMISDLAELAKLR 294

  Fly   197 DFPLSLYVIAIL-----PQLNYYEYVFIKTETREEAQKRFYRELREIEDKQEREIQGLETEAREM 256
            |.| .|..:.:|     .:.:|.:...::....|...|.||      ||....|.:.:....:|.
Mouse   295 DLP-KLRALVLLDNPCADETDYRQEALVQMAHLERLDKEFY------EDDDRAEAEEIRQRLKEE 352

  Fly   257 AEAD 260
            .:.|
Mouse   353 QDQD 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TbCMF46	NP_609325.2	PPP1R42	66..>190	CDD:455733	37/125 (30%)
		leucine-rich repeat	69..90	CDD:275378	2/20 (10%)
		leucine-rich repeat	91..112	CDD:275378	8/22 (36%)
		leucine-rich repeat	113..134	CDD:275378	5/20 (25%)
		leucine-rich repeat	135..156	CDD:275378	7/20 (35%)
		leucine-rich repeat	157..181	CDD:275378	6/23 (26%)
		SMC_prok_B	225..>530	CDD:274008	9/36 (25%)
Lrrc23	XP_006505721.1	LRR	<100..>266	CDD:443914	42/163 (26%)
		leucine-rich repeat	100..119	CDD:275380	3/9 (33%)
		leucine-rich repeat	120..141	CDD:275380	4/20 (20%)
		leucine-rich repeat	142..162	CDD:275380	4/22 (18%)
		leucine-rich repeat	163..183	CDD:275380	2/22 (9%)
		leucine-rich repeat	184..207	CDD:275380	8/22 (36%)
		PPP1R42	187..331	CDD:455733	42/147 (29%)
		leucine-rich repeat	208..228	CDD:275380	5/20 (25%)
		leucine-rich repeat	229..250	CDD:275380	7/20 (35%)
		leucine-rich repeat	251..273	CDD:275380	6/23 (26%)
		leucine-rich repeat	274..298	CDD:275380	10/24 (42%)