Protein Alignment CG4592 and ECHDC1

DIOPT Version :10

• Sequence 1: NP_609324.2
• Gene: CG4592 / 34317
• FlyBaseID: FBgn0032162
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_001132982.1
• Gene: ECHDC1 / 55862
• HGNCID: 21489
• Length: 307
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 82/325 - (25%)
• Similarity: 146/325 - (44%)
• Gaps: 72/325 - (22%)

  Fly     1 MLRNRLIDGVRRIKPILCGGQSLRSLANG---ATSKLT-------TIEVD-DRSGIATLSMNLPP 54
            :|:...:.|  |.|.:...|.||.|.::|   ...|.|       :|::. :.:||..|::|.|.
Human    11 LLKTASLSG--RTKLLHQTGLSLYSTSHGFYEEEVKKTLQQFPGGSIDLQKEDNGIGILTLNNPS 73

  Fly    55 -VNTLTMELMHDLIDSINQIES-NKSRGLILTSSNDKVFSAGLDLNEMLN----PDVERLRLFW- 112
             :|..:..:|..|::.:.::|: .:.:|||:..:.: .||:|.|||.:.:    .|...:.:|.
Human    74 RMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKN-TFSSGSDLNAVKSLGTPEDGMAVCMFMQ 137

  Fly   113 ---TRFQDLWLALHLCGLPTAAAINGHSPAAGCVLATACEYRVMLPNLFIGIHATRFSFVISKWM 174
               |||..|       .|.:.|.:.|.:...|....|||::|:|.|.       ::..||
Human   138 NTLTRFMRL-------PLISVALVQGWALGGGAEFTTACDFRLMTPE-------SKIRFV----- 183

  Fly   175 MNSYQSVLP-----RRIVE--------RALNQGKLFASQEALDVGLVDEIACSKEE--ALSKCAA 224
             :....::|     .|:||        :.|:......|:.||::|:|:|:..|.:|  :|.:...
Human   184 -HKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDETKSLEEAQE 247

  Fly   225 FIATFDKTNP-VARCLTKRMC--REPDVRELLQDRAADLKECVDYVTTPLFQEGLCAHLEGLKKR 286
            ::..|.:..| |.|.|.|.:|  ||..:.|.||:. .||...|         .|..|:||.:.|:
Human   248 WLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNE-RDLLGTV---------WGGPANLEAIAKK 302

  Fly   287  286
            Human   303  302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4592	NP_609324.2	crotonase-like	43..287	CDD:474030	70/272 (26%)
ECHDC1	NP_001132982.1	CaiD	61..300	CDD:440647	69/269 (26%)