Protein Alignment CG4592 and CDY1B

DIOPT Version :10

• Sequence 1: NP_609324.2
• Gene: CG4592 / 34317
• FlyBaseID: FBgn0032162
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_001003895.1
• Gene: CDY1B / 253175
• HGNCID: 23920
• Length: 554
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 55/299 - (18%)
• Similarity: 105/299 - (35%)
• Gaps: 90/299 - (30%)

  Fly    10 VRRIKPILCGGQ------------------SLRSLANGATSKLTTIEVDDRSGIATLSMNLPPVN 56
            |.|:|    |||                  ::|...:.:|.:...::.:|......||......|
Human   247 VPRVK----GGQRNITDDSRDQPFIKKMHFTIRLTESASTYRDIVVKKEDGFTQIVLSTRSTEKN 307

  Fly    57 TLTMELMHDLIDSINQIESNKSRGLILTSSNDKVFSAGLDLNEML-----NPDVERLRLFWT--R 114
            .|..|::.::::::|...::.|: |:|.|:...||..|||....:     |.:...|.:..|  .
Human   308 ALNTEVIKEIVNALNSAAADDSK-LVLFSAAGSVFCCGLDFGYFVKHLRNNRNTASLEMVDTIKN 371

  Fly   115 FQDLWLALHLCGLPTAAAINGHSPAAGCVLATACEYRVMLPNLFIGIHATRFSFVISKWMMNSYQ 179
            |.:.::...   .|...::||.:...|..:...|:.          :.|..     ..|....|.
Human   372 FVNTFIQFK---KPIVVSVNGPAIGLGASILPLCDL----------VWANE-----KAWFQTPYT 418

  Fly   180 S-----------VLPRRIVERALNQ----GKLFASQEALDVGLVDEIACS-----------KEEA 218
            :           ..|:.:.:.:.|:    |:...::||...|||.::..:           ||.|
Human   419 TFGQSPDGCSSITFPKMMGKASANEMLIAGRKLTAREACAKGLVSQVFLTGTFTQEVMIQIKELA 483

  Fly   219 ------LSKCAAFIATFDKTNPVARCLTKRMCREPDVRE 251
                  |.:|.|.:          ||..|....:.:.||
Human   484 SYNPIVLEECKALV----------RCNIKLELEQANERE 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4592	NP_609324.2	crotonase-like	43..287	CDD:474030	46/248 (19%)
CDY1B	NP_001003895.1	CD_CDY	5..56	CDD:349284
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..106
		crotonase-like	286..482	CDD:119339	37/214 (17%)