Protein Alignment CG4592 and Hibch

DIOPT Version :10

• Sequence 1: NP_609324.2
• Gene: CG4592 / 34317
• FlyBaseID: FBgn0032162
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_666220.1
• Gene: Hibch / 227095
• MGIID: 1923792
• Length: 385
• Species: Mus musculus
• Alignment Length: 305
• Identity: 64/305 - (20%)
• Similarity: 116/305 - (38%)
• Gaps: 48/305 - (15%)

  Fly     7 IDGVRRIKPILCGGQSLR-SLANGATSKLTTIEVDDRSGIATLSMNLPP-VNTLTMELMHDLIDS 69
            :...||...||   |.|| |:...|...|  :|.....|:.||  |.|. :|.|::.::..:...
Mouse    13 VSSFRRASVIL---QHLRMSMHTEAAEVL--LERRGCGGVITL--NRPKFLNALSLNMIRQIYPQ 70

  Fly    70 INQIESNKSRGL-ILTSSNDKVFSAGLDLNEMLNPDVERLRLFWTRFQDLWL---ALHLCGLPTA 130
            :...|.:....| |:..:..|.|.||.|:..:......|..|....|::.::   |:..|..|..
Mouse    71 LKTWEQDPDTFLIIIKGAGGKAFCAGGDIKALSEAKKARQNLTQDLFREEYILNNAIASCQKPYV 135

  Fly   131 AAINGHSPAAGCVLATACEYRV---------------MLPNLFIGIHATRFSFVISKWM-MNSYQ 179
            |.|:|.:...|..|:...::||               :.|::..|....|....:..:: :..|:
Mouse   136 ALIDGITMGGGVGLSVHGQFRVATERSLFAMPETGIGLFPDVGGGYFLPRLQGKLGYFLALTGYR 200

  Fly   180 SVLPRRIVERALNQGKLFASQEALDVGLVDEIACSKEEALSKCAAFIATFDKTNPVARCLTKRMC 244
              |..|.|.|| .....|...|.|.| |.:|:...|..:....|..:.::...:.:
Mouse   201 --LKGRDVHRA-GIATHFVDSEKLRV-LEEELLALKSPSAEDVAGVLESYHAKSKM--------- 252

  Fly   245 REPDVRELLQDRAADLKEC-----VDYVTTPLFQEGLCAHLEGLK 284
             :.|...:.::....:..|     |:.:...|.|:|....:|.:|
Mouse   253 -DQDKSIIFEEHMDKINSCFSANTVEQIIENLRQDGSPFAIEQMK 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4592	NP_609324.2	crotonase-like	43..287	CDD:474030	53/268 (20%)
Hibch	NP_666220.1	ECH_2	46..375	CDD:465024	53/267 (20%)