Protein Alignment CG4592 and ECI1

DIOPT Version :10

• Sequence 1: NP_609324.2
• Gene: CG4592 / 34317
• FlyBaseID: FBgn0032162
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_001910.2
• Gene: ECI1 / 1632
• HGNCID: 2703
• Length: 302
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 105/303 - (34%)
• Similarity: 161/303 - (53%)
• Gaps: 25/303 - (8%)

  Fly     6 LIDGVR-RIKPILCGGQSLRSLANGAT--------------SKLTTIEVDDRSGIATLSMNLPPV 55
            |:..|| ..:.:|..|..|...|.|.|              |:...:|.|..:|:|.:....|||
Human     3 LVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEPDAGAGVAVMKFKNPPV 67

  Fly    56 NTLTMELMHDLIDSINQIESNKS-RGLILTSSNDKVFSAGLDLNEMLNPDVERLRLFWTRFQDLW 119
            |:|::|.:.:|:.|:.::|::|| ||:||||....||||||||.||..........:|...|:||
Human    68 NSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCGRSPAHYAGYWKAVQELW 132

  Fly   120 LALHLCGLPTAAAINGHSPAAGCVLATACEYRVML--PNLFIGIHATRFSFVISKWMMNSYQSVL 182
            |.|:...|...:||||..||.||::|..|:||::.  |...||::.|:...:...|:.::.::.:
Human   133 LRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQLGIIAPFWLKDTLENTI 197

  Fly   183 PRRIVERALNQGKLFASQEALDVGLVDEIACSKE---EALSKCAAFIATFDKTNPVARCLTKRMC 244
            ..|..||||..|.||...|||.||:||::...::   .|||..|.::|..|.    ||.|||.|.
Human   198 GHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAIAQWMAIPDH----ARQLTKAMM 258

  Fly   245 REPDVRELLQDRAADLKECVDYVTTPLFQEGLCAHLEGLKKRK 287
            |:.....|:..|.||::..|.:::....|:.|..:||.||:.|
Human   259 RKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEEK 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4592	NP_609324.2	crotonase-like	43..287	CDD:474030	92/249 (37%)
ECI1	NP_001910.2	ECH_1	52..298	CDD:395302	91/249 (37%)