Protein Alignment CG4592 and Hibch

DIOPT Version :10

• Sequence 1: NP_609324.2
• Gene: CG4592 / 34317
• FlyBaseID: FBgn0032162
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: XP_312972.5
• Gene: Hibch / 1274008
• VectorBaseID: AGAMI1_007696
• Length: 387
• Species: Anopheles gambiae
• Alignment Length: 353
• Identity: 80/353 - (22%)
• Similarity: 134/353 - (37%)
• Gaps: 114/353 - (32%)

  Fly    13 IKPILCGGQSLRSLANGATSKLTTIEVDDRSGIATLSMNLP-PVNTLTMELMHDLIDSINQIESN 76
            :.|.:|  :::.|.|..:.|.:.|.||..: |:.||  |.| .:|.:.:|::..:.|::.|.||.
Mosquito    18 VAPSVC--RAMSSTAGDSNSLVLTEEVGSK-GVITL--NRPKALNAINLEMVRLIYDAMKQWEST 77

  Fly    77 KSRGLILTSSNDKVFSAGLD---LNEMLNPDVERLRLFWTRFQDLWLALHLCGL-----PT-AAA 132
            || .:|:.|..||.|.||.|   :.|..|.::.| :.|.|.::       |..|     || .|.
Mosquito    78 KS-VVIVKSVGDKAFCAGGDVRAITETSNVELAR-KFFSTEYR-------LNALIGSYRPTYIAF 133

  Fly   133 INGHSPAAGCVLATACEYRV------------------------MLP------NLFIGIHATRFS 167
            |:|.:...|..|:...:||:                        .||      .|::|:...|..
Mosquito   134 IDGITMGGGVGLSVHGKYRIATERTMFAMPETAIGLFPDVGGGYFLPRLEGKLGLYLGLTGFRLK 198

  Fly   168 ------------FVISKWMMNSYQSVLPRRI---VERALNQGKLFASQEALDVGLVDEIACSKE- 216
                        :|.||.:....|.:|....   ||..|::     ..|..|.|.  |...:|:
Mosquito   199 GRDVHKAGVATHYVESKNLAALEQQLLATTSGAEVESVLDR-----FSEKRDAGA--EFVLAKQL 256

  Fly   217 EALSKC-------AAF--------------IATFDKTNPVARCLTKRMCREPDVRELLQDRAADL 260
            :.:::|       |.|              :....|.:|.:..:|:        ::|......||
Mosquito   257 QQINQCFSAPTVEAIFQQLERDGSEWAQNTLKLLHKMSPTSMVVTQ--------KQLELGGKMDL 313

  Fly   261 KEC--------VDYVTTPLFQEGLCAHL 280
            |.|        |.:.....|:||:.|.|
Mosquito   314 KTCLKMEYRLAVHHAIDSDFKEGVRALL 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4592	NP_609324.2	crotonase-like	43..287	CDD:474030	72/323 (22%)
Hibch	XP_312972.5	ECH_2	46..367	CDD:465024	72/322 (22%)