Protein Alignment CG4592 and Cdyl

DIOPT Version :10

• Sequence 1: NP_609324.2
• Gene: CG4592 / 34317
• FlyBaseID: FBgn0032162
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_034011.1
• Gene: Cdyl / 12593
• MGIID: 1339956
• Length: 593
• Species: Mus musculus
• Alignment Length: 240
• Identity: 45/240 - (18%)
• Similarity: 78/240 - (32%)
• Gaps: 78/240 - (32%)

  Fly    56 NTLTMELMHDLIDSINQIESNKSRGLILTSSNDKVFSAGLD---LNEMLNPDVER--------LR 109
            |:|..|:|.::..:::...::.|: |:|.|:...||..|||   ....|..|.:|        :|
Mouse   360 NSLNPEVMKEVQSALSTAAADDSK-LVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMADAIR 423

  Fly   110 LFWTRFQDLWLALHLCGLPTAAAINGHSPAAGCVLATACEY------------------------ 150
            .|...|...       ..|...|:||.:...|..:...|:.
Mouse   424 NFVNTFIQF-------KKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCS 481

  Fly   151 RVMLPNLFIGIHATRFSFVISKWMMNSYQSVLPRRIVERALNQGKLFASQEALDVGLVDEI---- 211
            .||.|.:..|..|....|                        .|:...:|||...|||.::
Mouse   482 TVMFPKIMGGASANEMLF------------------------SGRKLTAQEACGKGLVSQVFWPG 522

  Fly   212 -----ACSKEEALSKCAAFIATFDKTNPVARCLTKRMCREPDVRE 251
                 ...:.:.|:.|...:  .:::..:.||..|....:.:.||
Mouse   523 TFTQEVMVRIKELASCNPVV--LEESKALVRCNMKMELEQANERE 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4592	NP_609324.2	crotonase-like	43..287	CDD:474030	45/240 (19%)
Cdyl	NP_034011.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		Interaction with EZH2. /evidence=ECO:0000250|UniProtKB:Q9Y232	56..304
		CD_CDY	57..106	CDD:349284
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..158
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..223
		crotonase-like	339..535	CDD:119339	38/206 (18%)
		Acetyl-CoA-binding domain. /evidence=ECO:0000255	357..589		45/240 (19%)