Protein Alignment CG4594 and ECHDC2

DIOPT Version :10

• Sequence 1: NP_609323.1
• Gene: CG4594 / 34316
• FlyBaseID: FBgn0032161
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_001185890.1
• Gene: ECHDC2 / 55268
• HGNCID: 23408
• Length: 292
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 71/260 - (27%)
• Similarity: 110/260 - (42%)
• Gaps: 45/260 - (17%)

  Fly    35 GIATLTMNRPPVNSQ--NVQLLLDLQTSISEIENNKSRGLILTSASSNVFSAGLDIFEMYNTD-- 95
            ||..:.||||...:.  ||.:...|:|.....|:.:.|.|:..|....||.||.|:.|.....
Human    41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEA 105

  Fly    96 -----VERLRTVWTELQNVWIALYGTTLPTAAAINGHAPAGGCLLATACEYRVMRPNFLIGLNEA 155
                 |:|||.:..:     ||.:  ..||.||::|.|..||..||.||:.||...:.::||.|.
Human   106 EVGVFVQRLRGLMND-----IAAF--PAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIET 163

  Fly   156 QLGIIAPKWLMSGFASILPK----RVAERALTQGRMFTTQEAFEVGLIDEIASSKEE---ALEKC 213
            ..|::..    :|....||:    .:|:..:..||..:..||..:||::...:..||   |.::.
Human   164 TRGLLPG----AGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRA 224

  Fly   214 AAFIGTFAKVNPLARGLTKLQF-RGDNIKEFEMIREKDIADFVALASSPGVQKVMGAYLENLKNK 277
            .|.........|:|..|.|:.. ||         .|.|||..:|:...        .|.:|:..:
Human   225 RALAQEILPQAPIAVRLGKVAIDRG---------TEVDIASGMAIEGM--------CYAQNIPTR 272

  Fly   278  277
            Human   273  272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4594	NP_609323.1	crotonase-like	35..280	CDD:474030	71/260 (27%)
ECHDC2	NP_001185890.1	crotonase-like	38..292	CDD:474030	71/260 (27%)