Protein Alignment CG4594 and HIBCH

DIOPT Version :10

• Sequence 1: NP_609323.1
• Gene: CG4594 / 34316
• FlyBaseID: FBgn0032161
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_055177.2
• Gene: HIBCH / 26275
• HGNCID: 4908
• Length: 386
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 60/282 - (21%)
• Similarity: 115/282 - (40%)
• Gaps: 35/282 - (12%)

  Fly     7 LRLMAHGAPSRLMSTATKLTTVEINDKTGIATLTMNRPP-VNSQNVQLLLDLQTSISEIENNKSR 70
            ||:..|       :.|.:...:|....||:  :|:|||. :|:..:.::..:...:.:.|.:...
Human    26 LRMSKH-------TDAAEEVLLEKKGCTGV--ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPET 81

  Fly    71 GL-ILTSASSNVFSAGLDIFEMYNTD--VERLRTVWTE----LQNVWIALYGTTLPTAAAINGHA 128
            .| |:..|....|.||.||..:...:  .:::..|:..    |.|   |:.....|..|.|:|..
Human    82 FLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNN---AVGSCQKPYVALIHGIT 143

  Fly   129 PAGGCLLATACEYRVMRPNFLIGLNEAQLGIIAPKWLMSGFASILPKRVAE----RALTQGRMFT 189
            ..||..|:...::||.....|..:.|..:|:...    .|....||:...:    .||| |....
Human   144 MGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPD----VGGGYFLPRLQGKLGYFLALT-GFRLK 203

  Fly   190 TQEAFEVGLIDEIASSKEEA-LEKCAAFIGTFAKVNPLARGLTKLQFRGDNIKEFEMIREKDIAD 253
            .::.:..|:......|::.| ||:....:.:.:|.| :|..|..........::...|.|:.:..
Human   204 GRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKEN-IASVLENYHTESKIDRDKSFILEEHMDK 267

  Fly   254 FVALASSPGVQKVMGAYLENLK 275
            ..:..|:..|:::    :|||:
Human   268 INSCFSANTVEEI----IENLQ 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4594	NP_609323.1	crotonase-like	35..280	CDD:474030	54/254 (21%)
HIBCH	NP_055177.2	ECH_2	46..376	CDD:465024	55/255 (22%)