Protein Alignment CG4594 and ECHS1

DIOPT Version :10

• Sequence 1: NP_609323.1
• Gene: CG4594 / 34316
• FlyBaseID: FBgn0032161
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_004083.3
• Gene: ECHS1 / 1892
• HGNCID: 3151
• Length: 290
• Species: Homo sapiens
• Alignment Length: 209
• Identity: 54/209 - (25%)
• Similarity: 92/209 - (44%)
• Gaps: 25/209 - (11%)

  Fly    30 INDKTG----IATLTMNRP-PVNSQNVQLLLDLQTSISEIENNKSRGLILTSASSNVFSAGLDIF 89
            |.:|.|    :..:.:||| .:|:....|:.:|..::...|.:.:.|.|:.:.....|:||.||.
Human    37 IAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIK 101

  Fly    90 EMYNTDVERLRTVWTELQNVWIALYGTTLPTAAAINGHAPAGGCLLATACEY-------RVMRPN 147
            ||.|...:...:  ::....|..|.....|..||:||:|..|||.||..|:.       :..:|.
Human   102 EMQNLSFQDCYS--SKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPE 164

  Fly   148 FLIGLNEAQLGIIAPKWLMSGFASILPKRVAERALTQGRMFTTQEAFEVGLIDEIASSK---EEA 209
            .|||......|       .......:.|.:|...:..|...:.|:|.:.||:.:|...:   |||
Human   165 ILIGTIPGAGG-------TQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEA 222

  Fly   210 LEKCAAFIGTFAKV 223
            :: ||..|.:.:|:
Human   223 IQ-CAEKIASNSKI 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4594	NP_609323.1	crotonase-like	35..280	CDD:474030	52/204 (25%)
ECHS1	NP_004083.3	crotonase-like	32..288	CDD:474030	54/209 (26%)