Protein Alignment CG4594 and Cdyl

DIOPT Version :10

• Sequence 1: NP_609323.1
• Gene: CG4594 / 34316
• FlyBaseID: FBgn0032161
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_034011.1
• Gene: Cdyl / 12593
• MGIID: 1339956
• Length: 593
• Species: Mus musculus
• Alignment Length: 254
• Identity: 57/254 - (22%)
• Similarity: 100/254 - (39%)
• Gaps: 45/254 - (17%)

  Fly    47 NSQNVQLLLDLQTSISEIENNKSRGLILTSASSNVFSAGLD---IFEMYNTDVERLRTVWTE-LQ 107
            ||.|.:::.::|:::|....:.|: |:|.||..:||..|||   .......|.:|..|...: ::
Mouse   360 NSLNPEVMKEVQSALSTAAADDSK-LVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMADAIR 423

  Fly   108 NVWIALYGTTLPTAAAINGHAPAGGCLLATACEYRVMRPNFLIGLNEAQLGIIAPKWLMSGFAS- 171
            |..........|...|:||.|...|..:...|:        ::..||       ..|..:.:.:
Mouse   424 NFVNTFIQFKKPIIVAVNGPAIGLGASILPLCD--------VVWANE-------KAWFQTPYTTF 473

  Fly   172 ----------ILPKRV----AERALTQGRMFTTQEAFEVGLIDEI---ASSKEEALEKCAAFIGT 219
                      :.||.:    |...|..||..|.|||...||:.::   .:..:|.:.:    |..
Mouse   474 GQSPDGCSTVMFPKIMGGASANEMLFSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVR----IKE 534

  Fly   220 FAKVNPLARGLTKLQFRGDNIKEFEMIREKDIADFVALASSPGVQKVMGAYLENLKNKV 278
            .|..||:....:|...|.:...|.|...|::..   .|....|..:.|.:.|:.|:.|:
Mouse   535 LASCNPVVLEESKALVRCNMKMELEQANERECE---VLKKIWGSAQGMDSMLKYLQRKI 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4594	NP_609323.1	crotonase-like	35..280	CDD:474030	57/254 (22%)
Cdyl	NP_034011.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		Interaction with EZH2. /evidence=ECO:0000250|UniProtKB:Q9Y232	56..304
		CD_CDY	57..106	CDD:349284
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..158
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..223
		crotonase-like	339..535	CDD:119339	43/194 (22%)
		Acetyl-CoA-binding domain. /evidence=ECO:0000255	357..589		56/251 (22%)